Efficacy of vaccination against pneumococcal infection in workers of metallurgical industry
https://doi.org/10.18093/0869-0189-2016-26-4-481-487
Abstract
The aim of this study was to evaluate efficacy of vaccination against pneumococcal infection using Pneumo23 vaccine in workers of metallurgical industry. Methods. The study involved workers of mining and metallurgical enterprises who exposed to occupational hazard factors regularly. The lung function was assessed using spyrometry. The severity of COPD was evaluated using the CAT questionnaire. Number and duration of day off periods due to respiratory diseases were also considered. All parameters were measured at baseline and in 12 and 24 months after vaccination. Results. The number of work off days due to respiratory diseases significant decreased in a year after vaccination with Pneumo 23 vaccine. Functional parameters and well-being improved and the impact of the disease on daily life decreased in 12 and 24 months after the vaccination. Conclusion. The results of the study confirmed the high efficacy and safety of vaccination with Pneumo 23 vaccine in workers of metallurgical enterprises.
About the Authors
L. V. Postnikova
Federal Research Institute of Occupational Health: 31, Budennogo av., Moscow, 105275, Russia
Russian Federation
Russian Federation
hD, Head of Department at Federal Research Institute of Occupational Health; tel.: (917) 552-68-21;
A. A. Sal'nikov
Healthcare Department, Metalloinvest LLC Management Company: 28, Rublevskoe roadway, Moscow, 121609, Russia
Russian Federation
Russian Federation
PhD, Head of Healthcare Department, Metalloinvest LLC Management Company; tel.: (495) 981-55-55
I. V. Buhtijarov
Federal Research Institute of Occupational Health: 31, Budennogo av., Moscow, 105275, Russia
Russian Federation
Russian Federation
MD, Professor, Head of Federal Research Institute of Occupational Health; tel.: (495) 365-02-09;
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Review
For citations:
Postnikova L.V., Sal'nikov A.A., Buhtijarov I.V. Efficacy of vaccination against pneumococcal infection in workers of metallurgical industry. PULMONOLOGIYA. 2016;26(4):481-487. (In Russ.) https://doi.org/10.18093/0869-0189-2016-26-4-481-487
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