Influenza vaccination in pregnancy: unresolved issues
https://doi.org/10.18093/0869-0189-2016-26-1-98-103
Abstract
Despite well-known influenza challenge problem and long-lasting experience of influenza vaccination, several aspects of this medical problem require being resolved. Pregnant women are one of the most important risk groups needed in influenza prevention. Inactivated influenza vaccines are proved to be safe, but vaccination coverage of pregnant women has still been low. Based on the immune system particularities in pregnancy, we discussed cell immune response to vaccination. Data on safety and efficacy of influenza vaccination in pregnancy has also been reviewed. This strategy could increase vaccination efficacy in pregnant women and help to develop an individualized approach for use of commercially available vaccines.
About the Authors
D. V. Pakhomov
I.I.Mechnikov Federal Research Vaccine and Serum Institute”, Russian Science Academy; 5A, Malyy Kazennyy per., Moscow, 105064, Russia
Russian Federation
Russian Federation
PhD, Senior Researcher at Laboratory of Preventive Vaccination And Immune Therapy of Allergic Diseases, Federal institution “I.I.Mechnikov Scientific and Research Vaccine and Serum Institute”, Russian Science Academy; tel.: (495)917-41-49
M. P. Kostinov
I.I.Mechnikov Federal Research Vaccine and Serum Institute”, Russian Science Academy; 5A, Malyy Kazennyy per., Moscow, 105064, Russia
Russian Federation
Russian Federation
MD, Professor, Head of Laboratory of Preventive Vaccination And Immune Therapy of Allergic Diseases, Federal institution “I.I.Mechnikov Scientific and Research Vaccine and Serum Institute”, Russian Science Academy; tel.: (495) 917-41-49;
E. A. Khromova
I.I.Mechnikov Federal Research Vaccine and Serum Institute”, Russian Science Academy; 5A, Malyy Kazennyy per., Moscow, 105064, Russia
Russian Federation
Russian Federation
Junior Researcher at Laboratory of Preventive Vaccination And Immune Therapy of Allergic Diseases, Federal institution “I.I.Mechnikov Scientific and Research Vaccine and Serum Institute”, Russian Science Academy; tel.: (495) 917-41-49
S. S. Semenova
Moscow State Regional Perinatal Center; 12, Entuziastov roadway, Balashikha, Moscow region, 143900, Russia
Russian Federation
Russian Federation
Junior Researcher, Obstetrician and Gynecologist, Moscow State Regional Perinatal Center; tel.: (495) 529-50-13
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Review
For citations:
Pakhomov D.V., Kostinov M.P., Khromova E.A., Semenova S.S. Influenza vaccination in pregnancy: unresolved issues. PULMONOLOGIYA. 2016;26(1):98-103. (In Russ.) https://doi.org/10.18093/0869-0189-2016-26-1-98-103
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