Osteoporosis in patients with chronic obstructive pulmonary disease
https://doi.org/10.18093/0869-0189-2016-26-1-46-51
Abstract
The aim of this study was to analyze the course of osteoporosis in elderly females with pulmonary diseases. Methods. The study involved females with postmenopausal osteoporosis who did not receive regular treatment with oral steroids. All patients underwent spirometry before and after inhalation of a bronchodilator, bone densitometry with assessment of bone mineral density (BMD) and T-score at the proximal thigh, the lumbal spine and the one third distal forearm. FRAX risk assessment score was also used. Results. We examined 79 patients (mean age, 66.9 ± 1.7 years). Female patients with chronic obstructive pulmonary disease (COPD) had significantly more frequent forearm fractures, significantly lower FEV1, BMD at the forearm, and T-score at the forearm compared to patients with asthma and patients without obstructive pulmonary diseases. Conclusions.COPD contributes to more severe course of postmenopausal osteoporosis.
About the Authors
I. E. Zhila
Academician I.P.Pavlov First Saint-Petersburg State Medical University, Healthcare Ministry of Russia: 6 / 8, L'va Tolstogo str., Saint-Petersburg, 197089, Russia
Russian Federation
Russian Federation
Pulmonologist at Clinics of Hospital Internal Medicine, State Institution “Academician I.P.Pavlov First Saint-Petersburg State Medical University”, Healthcare Ministry of Russia; PhD student at Department of General Medical Practice (Family Medicine), State Institution “Academician I.P.Pavlov First Saint-Petersburg State Medical University”, Healthcare Ministry of Russia; tel. / fax: (812) 338-66-97
E. O. Bogdanova
Academician I.P.Pavlov First Saint-Petersburg State Medical University, Healthcare Ministry of Russia: 6 / 8, L'va Tolstogo str., Saint-Petersburg, 197089, Russia
Russian Federation
Russian Federation
Junior Researcher at Research Institute of Nephrology, State Institution “Academician I.P.Pavlov First Saint-Petersburg State Medical University”, Healthcare Ministry of Russia; tel. / fax: (812) 338-66-97
O. V. Zhila
Academician I.P.Pavlov First Saint-Petersburg State Medical University, Healthcare Ministry of Russia: 6 / 8, L'va Tolstogo str., Saint-Petersburg, 197089, Russia
Russian Federation
Russian Federation
Therapeutist at Clinics of Hospital Internal Medicine, State Institution “Academician I.P.Pavlov First Saint-Petersburg State Medical University”, Healthcare Ministry of Russia; PhD student at Department of General Medical Practice (Family Medicine), State Institution “Academician I.P.Pavlov First Saint-Petersburg State Medical University”, Healthcare Ministry of Russia; tel. / fax: (812) 338-66-97
N. L. Shaporova
Academician I.P.Pavlov First Saint-Petersburg State Medical University, Healthcare Ministry of Russia: 6 / 8, L'va Tolstogo str., Saint-Petersburg, 197089, Russia
Russian Federation
Russian Federation
MD, Professor, Chief Family Physician of Leningrad region, Head of Department of General Medical Practice (Family Medicine), State Institution “Academician I.P.Pavlov First Saint-Petersburg State Medical University”, Healthcare Ministry of Russia; tel. / fax: (812) 338-66-97
O. V. Dudina
Academician I.P.Pavlov First Saint-Petersburg State Medical University, Healthcare Ministry of Russia: 6 / 8, L'va Tolstogo str., Saint-Petersburg, 197089, Russia
Russian Federation
Russian Federation
PhD, Associate Professor at Department of General Medical Practice (Family Medicine), State Institution “Academician I.P.Pavlov First Saint-Petersburg State Medical University”, Healthcare Ministry of Russia; tel. / fax: (812) 338-66-97
S. Ya. Batagov
Academician I.P.Pavlov First Saint-Petersburg State Medical University, Healthcare Ministry of Russia: 6 / 8, L'va Tolstogo str., Saint-Petersburg, 197089, Russia
Russian Federation
Russian Federation
MD, Professor at M.V.Chernorutskiy Department of Hospital Internal Medicine, State Institution “Academician I.P.Pavlov First Saint-Petersburg State Medical University”, Healthcare Ministry of Russia; tel. / fax: (812) 338-71-89
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Review
For citations:
Zhila I.E., Bogdanova E.O., Zhila O.V., Shaporova N.L., Dudina O.V., Batagov S.Ya. Osteoporosis in patients with chronic obstructive pulmonary disease. PULMONOLOGIYA. 2016;26(1):46-51. (In Russ.) https://doi.org/10.18093/0869-0189-2016-26-1-46-51
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