Preview

PULMONOLOGIYA

Advanced search

Application of low8intensity laser for adrenal stimulation in males with chronic obstructive pulmonary disease and hormonal disorders

https://doi.org/10.18093/0869-0189-2015-25-5-581-585

Abstract

The aim of this study was to investigate a role of adrenal function stimulation in patients with stage 3 chronic obstructive pulmonary disease (COPD).

Methods. Blood levels of cortisol, aldosterone and testosterone were measured in 82 males with severe COPD and in 25 healthy subjects. The study involved three patient groups: 41 patients with stage 3 COPD who received lowintensity infrared laser radiation with a frequency of 80 Hz applied on the adrenal gland area additionally to the standard therapy; 26 patients with stage 3 COPD who received standard therapy only and 15 patients with COPD who received standard therapy and a placebo exposure using a switched off laser device.

Results. A significant reduction in blood cortisol, aldosterone and testosterone levels in patients with stage 3 COPD was found. A role of adrenal function stimulation was confirmed in patients with stage 3 COPD.

Conclusion. Severity of adrenal hormonal disorders correlates directly to severity of COPD. Treatment of male patients with stage 3 COPD should include adrenal hormone correction using both medication and nonmedication on individual basis. The lowintensity laser radiation of adrenal area could significantly increase blood cortisol level and improve quality of life of the patients.

About the Authors

V. A. Nikitin
N.N.Burdenko Voronezh State Medical Academy, Healthcare Ministry of Russia: 10, Studencheskaya str., Voronezh, 394622, Russia
Russian Federation

PhD, Assistant Lecturer, Department of Therapy, Institute of Postgraduate Physician Training, N.N.Burdenko Voronezh State Medical Academy, Healthcare Ministry of Russia; tel.: (473)
2366831



L. V. Vasil'eva
N.N.Burdenko Voronezh State Medical Academy, Healthcare Ministry of Russia: 10, Studencheskaya str., Voronezh, 394622, Russia
Russian Federation

MD, Professor, Head of Department of Therapy, Institute of Postgraduate Physician Training, N.N.Burdenko Voronezh State Medical Academy, Healthcare Ministry of Russia; tel.: (473)
2366831



L. A. Titova
N.N.Burdenko Voronezh State Medical Academy, Healthcare Ministry of Russia: 10, Studencheskaya str., Voronezh, 394622, Russia
Russian Federation

MD, Head of Department of Nursing, Institute of Postgraduate Physician Training, N.N.Burdenko Voronezh State Medical Academy, Healthcare Ministry of Russia; tel.: (473) 2366831



References

1. Karadag F., Ozcan H., Karul A.B. et al. Sex hormone alter ations and systemic inflammation in chronic obstructive pulmonary disease. Int. J. Clin. Pract. 2007; 63: 275–281.

2. Chuchalin A.G., ed. Chronic Obstructive Pulmonary Disease: Federal Programme of Healthcare Ministry of Russia and Russian Respiratory Society. Moscow: Atmosfera; 2004 (in Russian).

3. Zelenkov N.K. Investigation of oxidative stress mechanisms in inflammation and antioxidant treatment: Diss. Novosibirsk; 2007 (in Russian).

4. Kazimirchuk V.K., Mal'tsev V.I. Antioxidant system and its function in human. Zdorov’ya Ukraїni. 2004; 13–14: 34–36 (in Russian).

5. Vladimirov Yu.A. Free radicals in biological systems. Sorosovskiy obrazovatel'nyy zhurnal. 2000; 6 (12): 13–19 (in Russian).

6. Vorontsova Z.A., Cherkasova Yu.B., Titova L.A. Change in peripheral endocrine glands hormone production after fractionated low dose gammaradiation. Vestnik novykh meditsinskikh tekhnologiy. 2011; 18 (2): 45–46 (in Russian).

7. Nikitin V.A. Hormone disorders in patients with chronic obstructive pulmonary disease and therapy with lowinten sity laser radiation: Diss. Voronezh, 2013 (in Russian).

8. Burdet L., de Muralt B., Schutz Y. et al. Administration of growth hormone to underweight patients with chronic obstructive pulmonary disease. A prospective, randomized, controlled study. Am. J. Respir. Crit. Care Med. 1997; 156: 1800–1806.

9. Debigare R., Marquis K., Cote C.H. et al. Catabolic / anabolic balance and muscle wasting in patients with COPD. Chest. 2003; 124: 83–89.

10. Titova L.A., Nikitin V.A., Vasil'eva L.V. A method for severity assessment in chronic obstructive pulmonary disease. Patent RF N 2516971. 2014 (in Russian).


Review

For citations:


Nikitin V.A., Vasil'eva L.V., Titova L.A. Application of low8intensity laser for adrenal stimulation in males with chronic obstructive pulmonary disease and hormonal disorders. PULMONOLOGIYA. 2015;25(5):581-585. (In Russ.) https://doi.org/10.18093/0869-0189-2015-25-5-581-585

Views: 809


ISSN 0869-0189 (Print)
ISSN 2541-9617 (Online)