Severe broncho6bronchiolitis obliterans associated with Stevens–Johnson syndrome
https://doi.org/10.18093/0869-0189-2015-25-4-497-500
Abstract
Pulmonary complications in Stevens Johnson syndrome (SJS) or toxic epidermal ecrolysis (TEN) are rare and mostly manifest as broncho bron chiolitis obliterans with poor prognosis. Recently, there is no effective therapy for this condition in patients with SJS / TEN. We described a case of SJS with progressive hypercapnic respiratory failure in 4.5 year boy who died despite an intensive treatment. herefore, lung transplantation should be considered at the early stage of this disease.
About the Authors
I. K. Asherova
State Clinical Children's Hospital N1: 12 / 76, Lenina av., Yaroslavl', 150003, Russia
Russian Federation
Russian Federation
MD, Head of Department of Pulmonology at State Clinical Children's Hospital N1; tel.: (903) 6382887
S. D. Popov
Institute of Cancer Research: 123, Old Brompton Road, London, SW7 3RP, United Kingdom
Russian Federation
Russian Federation
PhD, pathologist at Division of Molecular Pathology and Therapy of Cancer, Institute of Cancer Research, London, Great Britain; tel.: (44 774) 8586247
M. A. Myagkova
Yaroslavl' State Medical University; Healthcare Ministry of Russia: 5, Revolyutsionnaya, str., Yaroslavl', 150000, Russia
Russian Federation
Russian Federation
PhD, Associate Professor at Department of Pathology, Yaroslavl' State Medical University; tel.: (905) 6465700
N. A. Il'ina
I.I.Mechnikov State NorthWest Medical University, Healthcare Ministry of Russia: 41, Kirochnaya str., SaintPetersburg, 191015, Russia
Russian Federation
Russian Federation
PhD, Associate Professor at Department of Radiology, I.I.Mechnikov State NorthWest Medical University, Healthcare
Ministry of Russia; tel.: (921) 3232763
V. V. Tarakanova
State Clinical Children's Hospital N1: 12 / 76, Lenina av., Yaroslavl', 150003, Russia
Russian Federation
Russian Federation
pulmonologist at Department of Pulmonology, State Clinical Children's Hospital N1; tel.: (906) 6333779
A. V. Vybornov
State Clinical Children's Hospital N1: 12 / 76, Lenina av., Yaroslavl', 150003, Russia
Russian Federation
Russian Federation
endoscopist at State Clinical Children's Hospital N1; tel.: (903) 8251336
A. V. Vlasova
State Regional Clinical Children's Hospital: 27, Tutaevskoe shosse, Yaroslavl', 150042, Russia
Russian Federation
Russian Federation
PhD, Deputy Chief Medical Officer, clinical pharmacologist, pulmonologist at State Regional Clinical Children's Hospital;
tel.: (905) 1325629
References
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5. Finkelstein Y., Soon G., Acuna P. et al. Recurrence and outcomes of Stevens Johnson syndrome and toxic epidermal necrolysis in children. Pediatrics. 2011; 128: 723–728
Review
For citations:
Asherova I.K., Popov S.D., Myagkova M.A., Il'ina N.A., Tarakanova V.V., Vybornov A.V., Vlasova A.V. Severe broncho6bronchiolitis obliterans associated with Stevens–Johnson syndrome. PULMONOLOGIYA. 2015;25(4):497-500. (In Russ.) https://doi.org/10.18093/0869-0189-2015-25-4-497-500
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