Можно ли улучшить прогноз у больных хронической обструктивной болезнью легких?


https://doi.org/10.18093/0869-0189-2015-25-4-469-476

Полный текст:


Аннотация

По данным Всемирной организации здравоохранения (ВОЗ), хроническая обструктивная болезнь легких (ХОБЛ) занимает 3ю позицию (4,8 %) среди причин смерти в мире; ежегодно от ХОБЛ умирает примерно 2,8 млн человек. Около 50–80 % больных ХОБЛ умирает от респираторных причин, либо во время обострений основного заболевания, либо от опухолей легких (от 8,5 до 27 %), либо от нереспираторных проблем. К ключевым предикторам неблагоприятного прогноза ХОБЛ относятся возраст пациентов, тяжесть бронхиальной обструкции и легочной гиперинфляции, гипоксемия и гиперкапния, частые обострения, коморбидные состояния и т. п. Летальность среди больных ХОБЛ снижается в случае длительной кислородотерапии (при гипоксемии), неинвазивной вентиляции легких (при гиперкапнии), а также при трансплантации легких (при терминальных стадиях ХОБЛ). В случае применения современных бронхорасширяющих препаратов (тиотропия бромид) улучшаются функциональные параметры и снижается число обострений ХОБЛ.


Об авторе

С. Н. Авдеев
ФГБУ "НИИ пульмонологии" ФМБА России: 105077, Москва, ул. 11я Парковая, 32, корп. 4
Россия

д. м. н., проф., руководитель клинического отдела ФГУ "НИИ пульмонологии" ФМБА России; тел. / факс: (495) 4655264



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Дополнительные файлы

Для цитирования: Авдеев С.Н. Можно ли улучшить прогноз у больных хронической обструктивной болезнью легких?  Пульмонология. 2015;25(4):469-476. https://doi.org/10.18093/0869-0189-2015-25-4-469-476

For citation: Avdeev S.N. Is it possible to improve prognosis in patients with chronic obstructive pulmonary disease? Russian Pulmonology. 2015;25(4):469-476. (In Russ.) https://doi.org/10.18093/0869-0189-2015-25-4-469-476

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