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HIV infection and tuberculosis comorbidity: what is the cause of death?

https://doi.org/10.18093/0869-0189-2015-25-4-461-464

Abstract

The aim. The purpose of this study was to analyze causes of deaths of hospitalised HIV infected patients with tuberculosis.

Methods. Medical reports of patients with tuberculosis who died in a specialized hospital of Samara city in 2013 were analyzed using the total sampling method.

Results. Ninety per cent of deaths in hospitalised HIV infected TB patients were caused by end stage AIDS with the high proportion (82%) of miliary tuberculosis, involvement of multiple organs (53%) and drug dependence (88%).

Conclusion. Improving interaction of TB specialists and experts on HIV infec tion is needed to improve statistic analysis of morbidity of and mortality from tuberculosis and to reduce mortality from these comorbid diseases.

About the Authors

B. E. Borodulin
State Institution "Samara State Medical University", Healthcare Ministry of Russia: 89, Chapaevskaya str., Samara, 443099, Russia
Russian Federation

MD, Professor, Head of Department of Phthisiology and Pulmonology, State Institution "Samara State Medical University", Healthcare Ministry of Russia; tel.: (846) 3325735



E. A. Borodulina
State Institution "Samara State Medical University", Healthcare Ministry of Russia: 89, Chapaevskaya str., Samara, 443099, Russia
Russian Federation

MD, Professor, Department of Phthisiology and Pulmonology, State Institution "Samara State Medical University", Healthcare Ministry of Russia; tel.: (846) 3325735



E. S. Vdoushkina
State Institution "Samara State Medical University", Healthcare Ministry of Russia: 89, Chapaevskaya str., Samara, 443099, Russia
Russian Federation

Resident Physician at Department of Phthisiology and Pulmonology, State Institution "Samara State Medical University", Healthcare Ministry of Russia; tel.: (846) 3325735



T. N. Matkina
State Institution "Samara State Medical University", Healthcare Ministry of Russia: 89, Chapaevskaya str., Samara, 443099, Russia N.V.Postnikov Samara State Regional Clinical Antituberculosis Institution: 48, Pionerskaya str., Samara, 443099, Russia
Russian Federation

Applicant at Department of Phthisiology and Pulmonology, State Institution «Samara State Medical University», Health care Ministry of Russia, phthisiatrician at N.V.Postnikov Samara State Regional Clinical Antituberculosis Institution; tel.: (846) 3325735



References

1. Pokrovskiy V.V., ed. HIV infection and AIDS: national guidelines. Moscow: GEOTAR Media; 2013 (in Russian).

2. World Health Organization. Global tuberculosis control: WHO report 2011. WHO/HTM/TB/2011.16. Geneva: World Health Organization; 2011

3. Global tuberculosis control: WHO report 2012. Executive Summary. Available at: http://www.who.int/tb/publications/global_report/gtbr12_exec summary_ru.pdf (in Russian).

4. Shilova M.V. Tuberculosis in Russia in 2011. Moscow, Rostov on Don: Feniks; 2013 (in Russian).

5. Podlekareva D.N., Mocroft A., Post F.A. et al. Mortality from HIV and TB coinfections is higher in Eastern Europe than in Western Europe and Argentina. AIDS. 2009; 23: 2485–2495.

6. Frolova O.P., Polesskiy V.A., Novoselova O.A. et al. Tuberculosis in HIV infected patients as a national problem. Tuberkulez i bolezni legkikh. 2013; 10: 9–12 (in Russian).

7. Erokhin V.V., Kornilova Z.Kh., Alekseeva L.P. Detection, clinical manifestations and treatment of tuberculosis in HIV infected patients. Problemy tuberkuleza 2005; 10: 20–28 (in Russian).

8. Povalyaeva L.V., Borodulina E.A., Borodulin B.E. Newly diagnosed pulmonary tuberculosis and a diagnostic method. Tuberkulez i bolezni legkikh. 2011; 5: 113–114 (in Russian).

9. Borodulin B.E., Kurbatova E.V., Borodulina E.A., Povalyaeva L.V. Clinical and epidemiological characteristics of newly diagnosed pulmonary tuberculosis in relation to a diagnostic method. Tuberkulez i bolezni legkikh. 2007; 10: 17–19 (in Russian).

10. Bartlett J., Galant J., Pham P. Medical management of HIV infection. Translated from English. Moscow: R.Valent; 2012 (in Russian).

11. Pokrovskiy V.V., Ladnaya N.N., Sokolova E.V. HIV infection and tuberculosis in Russia: which is worse? Tuberkulez i bolezni legkikh. 2014; 6: 3–8 (in Russian).


Review

For citations:


Borodulin B.E., Borodulina E.A., Vdoushkina E.S., Matkina T.N. HIV infection and tuberculosis comorbidity: what is the cause of death? PULMONOLOGIYA. 2015;25(4):461-464. (In Russ.) https://doi.org/10.18093/0869-0189-2015-25-4-461-464

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ISSN 0869-0189 (Print)
ISSN 2541-9617 (Online)