Anti-epidemic activities to prevent pneumococcal infections in flooded areas of the Amur region
https://doi.org/10.18093/0869-0189-2015-25-3-303-311
Abstract
The aim of this study was to analyze CAP epidemiology and morbidity in the Amur region, to evaluate anti-epidemic measures for prevention of pneumococcal infections in flooded areas and medical and socioeconomic benefits of vaccination of children with risk factors for pneumococcal disease. Material and methods. Common morbidity of pneumonia was analyzed in the Amur region. To evaluate clinical and epidemiological efficacy of pneumococcal vaccination with PCV13 in 2014–2017, 5,000 children aged 2 to 5 yrs with high risk of pneumococcal infection were involved into a special follow-up programme. Clinical, epidemiological, social, hygienic, economic and statistical analyses were used. Results. The total incidence of pneumonia in population of the Amur region reached the peak value (897.3 per 100,000) in 2009; this was associated with influenza pandemic. CAP incidence decreased by 43.8% in 2010–2014. Morbidity of CAP had certain age-related and seasonal differences and was closely related to morbidity of acute respiratory viral infection. Results of microbiological monitoring of CAP pathogens in the Amur region were also discussed. Morbidity of pneumonia and acute respiratory infections decreased in 2014 in 69.4% of children vaccinated with PCV13. Morbidity of CAP reduced by 2,014 cases in 2014 that prevented economic loss of 94 billion RUB. Conclusion. Clinical and economic monitoring of CAP and pneumococcal vaccination with PCV13 in the Amur region have significant medical and socioeconomic efficacy.
About the Authors
A. G. Chuchalin
Federal Institution "Pulmonology Research Institute", Federal Medical and Biological Agency of Russia: 32, build. 4, 11th Parkovaya str., Moscow, 105077, Russia;
Russian Federation
Russian Federation
MD, Professor, Academician of Russian Science Academy, Director of Federal Institution "Pulmonology Research Institute", Federal Medical and Biological Agency of Russia; tel.: (495) 465-52-64;
G. G. Onishchenko
Russian Science Academy: 14, Leninskiy av., Moscow, 119991, Russia;
Russian Federation
Russian Federation
MD, Academician of Russian Science Academy, Professor, Assistant of Prime Ministry; tel.: (495) 985-40-30;
V. P. Kolosov
Federal Institution "Far Eastern Scientific Center of Physiology and Respiratory Pathology", Northern Department of Russian Academy of Medical Science: 22, Kalinina str., Blagoveshchensk, 675000, Russia;
Russian Federation
Russian Federation
MD, Professor, Associate Member of Russian Science Academy, Director of Federal institution "Far Eastern Scientific Center of Physiology and Respiratory Pathology", Northern Department of Russian Academy of Medical Science; tel.: (416) 277-28-00;
O. P. Kurganova
Federal Service on Customers Rights Protection and Human Well-being Surveillance in the Amur region: 30, Pervomayskaya str., Blagoveshchensk, 675002, Russia;
Russian Federation
Russian Federation
Head of Federal Service on Customers Rights Protection and Human Well-being Surveillance in the Amur region; tel.: (416) 252-56-29;
N. L. Tezikov
Healthcare Ministry of the Amur region; 135, Lenina str., Blagoveshchensk, 675023, Russia;
Russian Federation
Russian Federation
Health Minister of the Amur region; tel.: (416) 259-60-12;
L. G. Manakov
Federal Institution "Far Eastern Scientific Center of Physiology and Respiratory Pathology", Northern Department of Russian Academy of Medical Science: 22, Kalinina str., Blagoveshchensk, 675000, Russia;
Russian Federation
Russian Federation
MD, Professor, Academic Secretary of Federal institution "Far Eastern Scientific Center of Physiology and Respiratory Pathology", Northern Department of Russian Academy of Medical Science; tel.: (914) 589-00-66;
M. P. Gulevich
Healthcare Ministry of the Amur region; 135, Lenina str., Blagoveshchensk, 675023, Russia;
Russian Federation
Russian Federation
First Deputy Health Minister of the Amur region; tel.: (416) 220-07-65;
O. E. Trotsenko
Federal Institution “Khabarovsk Scientific and Research Institute of Epidemiology and Microbiology”, Federal Service on Customers Rights Protection and Human Well-being Surveillance: 2, Shevchenko str., Khabarovsk, 680610, Russia;
Russian Federation
MD, Director of Federal Institution “Khabarovsk Scientific and Research Institute of Epidemiology and Microbiology”, Federal Service on Customers Rights Protection and Human Well-being Surveillance; tel. (4212) 32-52-28;
Russian Federation
MD, Director of Federal Institution “Khabarovsk Scientific and Research Institute of Epidemiology and Microbiology”, Federal Service on Customers Rights Protection and Human Well-being Surveillance; tel. (4212) 32-52-28;
A. A. Perepelitsa
Federal Service on Customers Rights Protection and Human Well-being Surveillance in the Amur region: 30, Pervomayskaya str., Blagoveshchensk, 675002, Russia;
Russian Federation
Deputy Head of Federal Service on Customers Rights Protection and Human Well-being Surveillance in the Amur region; tel.: (416) 259-68-53;
Russian Federation
Deputy Head of Federal Service on Customers Rights Protection and Human Well-being Surveillance in the Amur region; tel.: (416) 259-68-53;
Yu. M. Perel'man
Federal Institution "Far Eastern Scientific Center of Physiology and Respiratory Pathology", Northern Department of Russian Academy of Medical Science: 22, Kalinina str., Blagoveshchensk, 675000, Russia;
Russian Federation
Russian Federation
MD, Professor, Deputy Director of Federal institution "Far Eastern Scientific Center of Physiology and Respiratory Pathology", Northern Department of Russian Academy of Medical Science; tel.: 8-416-277-28-00;
I. I. Pavlova
Federal Service on Customers Rights Protection and Human Well-being Surveillance in the Amur region: 30, Pervomayskaya str., Blagoveshchensk, 675002, Russia;
Russian Federation
Head of Department of Epidemiological Surveillance, Federal Service on Customers Rights Protection and Human Well-being Surveillance at the Amur region; tel.: (416) 259-68-87;
Russian Federation
Head of Department of Epidemiological Surveillance, Federal Service on Customers Rights Protection and Human Well-being Surveillance at the Amur region; tel.: (416) 259-68-87;
E. N. Burdinskaya
Federal Institution “Center of Hygiene and Epidemiology in the Amur region”: 30, Pervomayskaya str., Blagoveshchensk, 675002, Russia;
Russian Federation
Russian Federation
Head of Department of Epidemiological Surveillance, Federal Institution “Center of Hygiene and Epidemiology at the Amur region; tel.: 8-416-259-68-60;
N. A. Lipskaya
State Institution “Amur Regional Center of prevention and control of AIDS and infectious diseases”: 36, Shimanovskogo str., Blagoveshchensk, 675000, Russia
Russian Federation
Russian Federation
Hospital Chief Executive Officer of -State Institution “Amur Regional Center of prevention and control of AIDS and infectious diseases”; tel.: (416) 244-00-37;
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Review
For citations:
Chuchalin A.G., Onishchenko G.G., Kolosov V.P., Kurganova O.P., Tezikov N.L., Manakov L.G., Gulevich M.P., Trotsenko O.E., Perepelitsa A.A., Perel'man Yu.M., Pavlova I.I., Burdinskaya E.N., Lipskaya N.A. Anti-epidemic activities to prevent pneumococcal infections in flooded areas of the Amur region. PULMONOLOGIYA. 2015;25(3):303-311. (In Russ.) https://doi.org/10.18093/0869-0189-2015-25-3-303-311
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