A case of chronic sarcoidosis: current issues of therapy
https://doi.org/10.18093/0869-0189-2015-25-2-232-238
Abstract
We presented a clinical case of 43-year woman with relapsing course of sarcoidosis affecting the lungs and the skin. The diagnosis was confirmed by biopsy. The initial treatment included systemic corticosteroids which then were withdrawn due to insufficient efficacy with subsequent administration of methotrexate. This case demonstrates a personalized approach to treatment based on modern clinical guidelines and highlights difficulty to develop standard therapeutic strategy for a disease with unknown etiology.
About the Author
I. Yu. Vizel
State Institution Kazan State Medical University, Healthcare Ministry of Russia; 49, Butlerova ul., Kazan', 420012, Tatarstan Republik, Russia
Russian Federation
Russian Federation
PhD, Assistant Lecturer at the Department of Phthisiology and Pulmonology, State Institution Kazan State Medical University, Healthcare Ministry of Russia; tel.: 8-903-388-71-64;
References
1. Chuchalin A.G., Vizel' A.A., Il'kovich M.M. et al. Diagnosis and treatment of sarcoidosis Federal Clinical Guidelines. Moscow, Rossiyskoe respiratornoe obshchestvo; 2014. Available at: www.pulmonology.ru (in Russian).
2. Vorselaars A.D., van Moorsel C.H., Deneer V.H., Grutters J.C. Current therapy in sarcoidosis, the role of existing drugs and future medicine. Inflam. Allergy Drug Targets. 2013; 12 (6): 369–377.
3. Stepanyan I.E. Sarcoidosis in therapeutic practice. Doktor.Ru. 2014; 2 (90): 17–22 (in Russian).
4. Park M.K., Fontana Jr., Babaali H. et al. Steroid-sparing effects of pentoxifylline in pulmonary sarcoidosis. Sarcoid. Vasc. Diffuse Lung Dis. 2009; 26 (2): 121–131.
5. Cremers J.P., Drent M., Bast A. et al. Multinational evidence-based World Association of Sarcoidosis and Other Granulomatous Disorders recommendations for the use of methotrexate in sarcoidosis: integrating systematic literature research and expert opinion of sarcoidologists worldwide. Curr. Opin. Pulm. Med. 2013; 19 (5): 545–561.
6. Vizel' A.A., Amirov N.B. Sarcoidosis and digestive system injury. Vestnik sovremennoy klinicheskoy meditsiny. 2010; 3 (1): 43–50 (in Russian).
7. Vizel' I.Yu. Sarcoidosis: possibility of spontaneous regression. Vestnik sovremennoy klinicheskoy meditsiny. 2012; 5 (2): 54–60 (in Russian).
8. Vizel' A.A., Yaushev M.F. A case of effective treatment of pulmonary sarcoidosis using an inhaled steroid. In: The 8th Russian National Congress on Respiratory Disease. Abstract book. Moscow, Pul'monologiya; 1998. XLVIII.5: 387 (in Russian).
9. Vizel' I.Yu., Shmelev E.I., Baranova O.P.et al. Multicenter retrospective analysis of sarcoidosis. Klinicheskaya meditsina. 2014; 6: 28–34 (in Russian).
Review
For citations:
Vizel I.Yu. A case of chronic sarcoidosis: current issues of therapy. PULMONOLOGIYA. 2015;25(2):232-238. (In Russ.) https://doi.org/10.18093/0869-0189-2015-25-2-232-238
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