Chronic cough hypersensitivity syndrome
https://doi.org/10.18093/0869-0189-2015-25-2-224-228
Abstract
This article contains a review of a new concept of chronic cough. Recently, specific TRP receptors were investigated and the key role of increased sensitivity of these receptors for chronic cough development was described. Recent scientific data underlay a pathogenic concept of chronic cough as an independent pathological entity referred to as chronic cough hypersensitivity syndrome. Gender and age-related difference in pathogenesis and prevalence of chronic cough and cough receptor hypersensitivity have also reviewed in the article.
About the Author
S. Yu. Chikina
Federal Institution «Pulmonology Research Institute», Federal Medical and Biological Agency of Russia; 32, build. 4, 11th Parkovaya ul., Moscow, 105077, Russia
Russian Federation
Russian Federation
PhD, Senior Researcher of Laboratory of Functional and Ultrasound Investigations, Federal Institution "Pulmonology Research Institute", Federal Medical and Biological Agency of Russia, tel.: (495) 465
References
1. Morice A. Chronic cough: epidemiology. Chron. Respir. Dis. 2008; 5 (1): 43–47.
2. Morice A.H., McGarvey L., Pavord I. et al. Recommendations for the management of cough in adults. Thorax. 2006; 61 (Suppl. 1): i1–24.
3. Ford A.C., Forman D., Moayyedi P., Morice A.H. Cough in the community: a cross sectional survey and the relationship to gastrointestinal symptoms. Thorax/ 2006; 61 (11): 975–999.
4. Plevkova J. Cough is a gender issue. Доклад на ежегодном Конгрессе Европейского респираторного общества. Мюнхен; 2014.
5. Morice A.H. Chronic cough hypersensitivity syndrome. Cough. 2013; 9: 14–17.
6. Morice A.H. The cough hypersensitivity syndrome: a novel paradigm for understanding cough. Lung. 2010; 188: 587–590.
7. Morice A.H., Millqvist E., Belvisi M.G. et al. Expert opinion on the cough hypersensitivity syndrome in respiratory medicine. Eur. Respir. J. 2014; 44 (5): 1132–1148.
8. Song W.J., Chang Y.S., Morice A.H. Changing the paradigm for cough: does 'cough hypersensitivity' aid our understanding? Asia Pac. Allergy. 2014; 4 (1): 3–13.
9. Morice A.H. Cough and sputum. In: Palange P., Simonds A.K., eds. Respiratory Medicine. ERS Handbook. European Respiratory Society; 2013.
10. Groneberg D.A., Niimi A., Dinh Q.T. et al. Increased expression of transient receptor potential vanilloid-1 in airway nerves of chronic cough. Am. J. Respir. Crit. Care Med. 2004; 170: 1276–1280.
11. Sadofsky L.R., Ramachandran R., Crow C. et al. Inflammatory stimuli up-regulate transient receptor potential vanilloid-1 expression in human bronchial fibroblasts. Exp. Lung Res. 2012; 38 (2): 75–81.
12. Smit L.A., Kogevinas M., Anto J.M. et al. Transient receptor potential genes, smoking, occupational exposures and cough in adults. Respir. Res. 2012; 13: 26.
13. Niimi A., Brightling C.E., Dicpinigaitis P.V. Cough in asthma is due to eosinophilic airway inflammation: a Pro/Con Debate. Lung. 2014; 192 (1): 33–38.
14. McGarvey L.P., Butler C.A., Stokesberry S. et al. Increased expression of bronchial epithelial transient receptor potential vanilloid 1 channels in patients with severe asthma. J. Allergy Clin. Immunol. 2014; 133 (3): 704–712.
15. Plevkova J., Song W.J. Chronic cough in subjects with upper airway diseases: analysis of mechanisms and clinical applications. Asia Pac. Allergy 2013; 3: 127–135.
16. Morice A.H. Chronic cough: diagnosis, treatment and psychological consequences. Breathe. 2006; 3 (2): 165–174.
17. Chang A.B., Lasserson T.J., Gaffney J. et al. Gastro-oesophageal reflux treatment for prolonged non-specific cough in children and adults. Cochrane Database Syst. Rev. 2011. doi: 10.1002/14651858.CD004823.pub4.
18. Patberg K.W. The female preponderance to cough hypersensitivity syndrome: another clue pointing to the role of TRPV1 in cough. Lung. 2011; 189: 257–258.
19. Song W.J., Kim J.Y., Jo E.J. et al. Capsaicin cough sensitivity is related to the older female predominant feature in chronic cough patients. Allergy Asthma Immunol. Res. 2014; 6 (5): 401–408.
20. Derbyshire S.W., Nichols T.E., Firestone L. et al. Gender differences in patterns of cerebral activation during equal experience of painful laser stimulation. J. Pain. 2002; 3: 401–411.
21. Paulson P.E., Minoshima S., Morrow T.J., Casey K.L. Gender differences in pain perception and patterns of cerebral activation during noxious heat stimulation in humans. Pain. 1998; 76: 223–229.
22. Moulton E.A., Keaser M.L., Gullapalli R.P. et al. Sex differences in the cerebral BOLD signal response to painful heat stimuli. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2006; 291: R257–267.
23. Chung K.F., McGarvey L., Mazzone S.B. Chronic cough as a neuropathic disorder. Lancet Respir. Med. 2013; 1: 414–422.
24. Morice A.H., Fontana G.A., Sovijarvi A.R. et al. ERS Task Force. The diagnosis and management of chronic cough. Eur. Respir. J. 2004; 24: 481–492.
25. Song W.J., Morice A.H., Kim M.H. et al. Cough in the elderly population: relationships with multiple comorbidity. PLoS One 2013; 8 (10): e78081.
Review
For citations:
Chikina S.Yu. Chronic cough hypersensitivity syndrome. PULMONOLOGIYA. 2015;25(2):224-228. (In Russ.) https://doi.org/10.18093/0869-0189-2015-25-2-224-228
Views:
1693
Email this article 