Challenges in targeted therapy for cystic fibrosis in a patient with the complex allele [L467F; F508del]: from failure of first-line modulator therapy to successful use of vanzacaftor+tezacaftor+deutivacaftor combination

A. V. Nistarova; S. I. Petrova; Yu. V. Peshekhonova; A. A. Kuznetsova; А. В. Нистарова; С. И. Петрова; Ю. В. Пешехонова; А. А. Кузнецова

PULMONOLOGIYA
Russian Pulmonology Journal

ISSN 0869-0189 (Print)
ISSN 2541-9617 (Online)

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Nistarova A.V., Petrova S.I., Peshekhonova Yu.V., Kuznetsova A.A. Challenges in targeted therapy for cystic fibrosis in a patient with the complex allele [L467F; F508del]: from failure of first-line modulator therapy to successful use of vanzacaftor+tezacaftor+deutivacaftor combination. PULMONOLOGIYA. 2026;36(5):865-870. (In Russ.) https://doi.org/10.18093/0869-0189-2026-36-5-865-870

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ISSN 0869-0189 (Print)
ISSN 2541-9617 (Online)

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About the Authors

A. V. Nistarova
Federal State Budgetary Educational Institution of Higher Education Saint Petersburg State Pediatric Medical University of the Ministry of Health of the Russian Federation
Russian Federation

Anastasia V. Nistarova, Candidate of Medicine, Associate Professor, Department of Faculty Pediatrics

ul. Litovskaya 2, Saint-Petersburg, 194100 tel.: (812) 416-5272

S. I. Petrova
Federal State Budgetary Educational Institution of Higher Education Saint Petersburg State Pediatric Medical University of the Ministry of Health of the Russian Federation
Russian Federation

Svetlana I. Petrova, Candidate of Medicine, Associate Professor, Department of Faculty Pediatrics

ul. Litovskaya 2, Saint-Petersburg, 194100 tel.: (812) 416-52-72

Yu. V. Peshekhonova
Federal State Budgetary Educational Institution of Higher Education Saint Petersburg State Pediatric Medical University of the Ministry of Health of the Russian Federation
Russian Federation

Yulia V. Peshekhonova, Candidate of Medicine, Head of Pediatric Department No.2 of the Clinic,

ul. Litovskaya 2, Saint-Petersburg, 194100 tel.: (812) 416-52-72

A. A. Kuznetsova
Federal State Budgetary Educational Institution of Higher Education Saint Petersburg State Pediatric Medical University of the Ministry of Health of the Russian Federation
Russian Federation

Alla A. Kuznetsova, Doctor of Medicine, Professor of the Department of Faculty Pediatrics

ul. Litovskaya 2, Saint-Petersburg, 194100 tel.: (812) 416-52-72

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