Efficacy of immunization against pneumococcal infection in aluminum industry workers
https://doi.org/10.18093/0869-0189-2014-0-6-56-59
Abstract
Respiratory diseases are the leading cause of morbidity of aluminum industry workers. Aim. Given this fact the authorities of LLC RUSAL decided to vaccinate aluminum industry workers using PPV. Methods. This study included 200 workers (157 males) with a history of frequent (three or more episodes per a year) acute respiratory infection (ARI) or community-acquired pneumonia (CAP) or with stable COPD. The participants' age was 22 to 65 years, the length of work was 2 to 44 years. Results. In a year after the vaccination, there was 5-fold decrease in frequencies of both ARI episodes and COPD exacerbations. The average duration of exacerbations decreased from 23.7 ± 2.5 to 14.8 ± 1.3 days. No-one case of CAP was diagnosed in vaccinated patients during 12 months after the vaccination. Conclusion. Vaccination with a single-dose PPV-23 could reduce respiratory morbidity both in term of rate and duration of COPD exacerbations. Vaccination was safe and effective.
About the Authors
V. L. Spiridonov
LLC Medical Center RUSAL: 40, Pogranichnikov ul., Krasnoyarsk, 660111, Russia
Russian Federation
Russian Federation
PhD, Head of Occupational Medicine Department, LLC Medical Center RUSAL; tel.: (495) 720-51-70, ext. 52-99
N. A. Roslaya
State Institution of Sverdlovsk region "Sverdlovsk regional clinical hospital N 1": 189, Volgogradskaya ul., Ekaterinburg, 62000, Russia
Russian Federation
Russian Federation
MD, occupational physician, State Budget Healthcare Institution of Sverdlovsk region "Sverdlovsk regional clinical hospital N1"; tel.: (343) 351-02-89
K. A. Akopyan
LLC Medical Center RUSAL: 40, Pogranichnikov ul., Krasnoyarsk, 660111, Russia
Russian Federation
Russian Federation
Deputy Chief Medical Officer, LLC Medical Center RUSAL; tel.: (391) 256-44-19
T. V. Bushueva
Federal Institution "Ekaterinburg Medical and Scientific Center of Disease Prevention and Healthcare of Industrial Workers", Federal Service for Supervision of Consumer Rights Protection and Human Welfare: 30, Popova ul., Ekaterinburg, 620014, Russia
Russian Federation
Russian Federation
PhD, immunologist, Federal State Budget Scientific institution "Ekaterinburg Medical and Scientific Center of Disease Prevention and Healthcare of Industrial Workers", Federal Service for Supervision of Consumer Rights Protection and Human Welfare; tel.: (343) 371-87-54
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Review
For citations:
Spiridonov V.L., Roslaya N.A., Akopyan K.A., Bushueva T.V. Efficacy of immunization against pneumococcal infection in aluminum industry workers. PULMONOLOGIYA. 2014;(6):56-59. (In Russ.) https://doi.org/10.18093/0869-0189-2014-0-6-56-59
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