Etiological agerelated description of communityacquired pneumonia in children
https://doi.org/10.18093/0869-0189-2014-0-5-62-66
Abstract
Aim. The study was aimed at investigation of etiology of communityacquired pneumonia (CAP) in children in relation to age.
Methods.
Chlamydophila pneumoniae, Mycoplasma pneumoniaе, respiratory viruses, Epstein–Barr virus, cytomegalovirus and human herpes virus type 6 were searched using bacteriological, serological and molecular methods.
Results. We examined 145 hospitalized children aged 1 month to 17 years with
respiratory infection complicated by moderate CAP. Viruses were detected in 62 % of children under 4 years old, in 43 % of children of 4 to 7 years old and in 17 % of schoolage children. A rate of mixed viralbacterial CAP decreased with aging and was found in 30 % of children under 4 years old and in 4 % of schoolage children.
Conclusion. Viral infection, mainly respiratory syncytial virus and cytomegalovirus, prevailed in the etiology of CAP in children under 4 years; C. pneumoniae and M. pneumoniae prevailed in schoolage children.
About the Authors
A. S. Levina
Federal Institute of Childhood Infections; Saint-Petersburg, Russia
Saint-Petersburg State Medical Pediatric University, Healthcare Ministry or Russia; Saint-Petersburg, Russia
Russian Federation
Russian Federation
I. V. Babachenko
Federal Institute of Childhood Infections; Saint-Petersburg, Russia
Saint-Petersburg State Medical Pediatric University, Healthcare Ministry or Russia; Saint-Petersburg, Russia
Russian Federation
Russian Federation
E. V. Sharipova
Federal Institute of Childhood Infections; Saint-Petersburg, Russia
Russian Federation
Russian Federation
O. M. Ibragimova
Federal Institute of Childhood Infections; Saint-Petersburg, Russia
Russian Federation
Russian Federation
A. S. Kvetnaya
Federal Institute of Childhood Infections; Saint-Petersburg, Russia
Russian Federation
Russian Federation
O. S. Kalinogorskaya
Federal Institute of Childhood Infections; Saint-Petersburg, Russia
Russian Federation
Russian Federation
E. A. Murina
Federal Institute of Childhood Infections; Saint-Petersburg, Russia
Russian Federation
Russian Federation
V. V. Gostev
Federal Institute of Childhood Infections; Saint-Petersburg, Russia
Russian Federation
Russian Federation
References
1. UNICEF / WHO Pneumonia: The forgotten killer of children, 2006. http://whqlibdoc.who.int/publications/ 2006/9280640489_eng.pdf
2. Morbidity of Russian population in 2000–2009. Statistic data of Healthcare and Social Development Ministry of Russian Federation (in Russian).
3. Mizernitskiy Yu.L., Tsaregorodtsev A.D. Childhood pulmonology: problems and solutions. Issue 11. Moscow; ID "MedpraktikaM"; 2011 (in Russian).
4. Tatochenko V.K. Childhood pneumonia: diagnosis and treatment. Lechashchiy vrach. 2008; 8: 5–9 (in Russian).
5. Communityacquired pneumonia in children: prevalence, diagnosis, treatment, prevention (Scientific and Technical Program). Moscow; 2011 (in Russian).
6. Zhernosek V.F., Orynbasarova K. K., Batyrkhanov Sh.K. Pneumonia in children: treatment and prevention. Minsk; BelMAPO; 2013 (in Russian).
7. Malakhov A.B., Dronov I.A., Volkov I.K. et al. An optimal choice of therapy in communityacquired pneumonia. Pediatriya 2011; 1: 50–53 (in Russian).
8. Tatochenko V.K., Baranov A.A., eds. Clinical recomenda tions. Pediatrics (Pneumonia in children). Moscow; GEOTAR Media; 2005 (in Russian).
9. Samsygina G.A. Dudina T.A. Respiratory infection in infants. Moscow; Izdvo "Miklosh"; 2006 (in Russian).
10. Kim S.S., Spichak T.V., Yatsyshina S.B. et al. A role of virus es for communityacquired pneumonia in children. Voprosy diagnostiki v pediatrii. 2012; 4 (4): 21–25 (in Russian).
11. Harris M., Clark J., Coote N. et al. Guidelines for the man agement of community acquired pneumonia in children: update 2011. Thorax. 2011; 66: 1–23.
12. Ostapchuk M., Roberts D.M., Haddy R. Community Acquired Pneumonia in Infants and Children. Am. Fam. Physician. 2004; 70 (5): 899–908.
13. Marx J.A., Hockberger R.S., Walls R.M. Pneumonia. In Rosen's Emergency Medicine. 8. Philadelphia; Mosby / Else vier; 2013. 978–987.
14. Kliegman R.M., Behrman R.E., Jenson H.B. et al. CommunityAcquired Pneumonia. In Nelson Textbook of Pedia trics. 9. Elsevier; 2011. 1474–1479.
Review
For citations:
Levina A.S., Babachenko I.V., Sharipova E.V., Ibragimova O.M., Kvetnaya A.S., Kalinogorskaya O.S., Murina E.A., Gostev V.V. Etiological agerelated description of communityacquired pneumonia in children. PULMONOLOGIYA. 2014;(5):62-66. (In Russ.) https://doi.org/10.18093/0869-0189-2014-0-5-62-66
Views:
1281
Email this article 