Tuberous sclerosis with lung involvement
https://doi.org/10.18093/0869-0189-2023-33-6-849-855
Abstract
Relevance. Tuberous sclerosis complex (TSC) is a rare genetically determined disease from the group of phakomatoses, which is characterized by a wide range of damage to organs and systems, a variety of clinical manifestations and a progressive course, leading to disability of patients and a reduction in life expectancy. Benign tumors (hamartomas) can occur with TSC in various organs, including the brain, eyes, skin, heart, kidneys, liver, lungs, gastrointestinal tract, endocrine, and skeletal systems. Gradually progressing and increasing in size, they disrupt the functions of these organs, sometimes leading to fatal consequences. Objective. Demonstration of clinical observation of TSC, the main manifestation of which was lung damage. Conclusion. The presented clinical case demonstrates the difficulty of diagnosing TSC, the features of its relatively benign course.
Keywords
tuberous sclerosis complex,
lymphangioleiomyomatosis,
multifocal micronodular pneumocyte hyperplasia
Supporting agencies: The publication had no financial support
About the Authors
N. V. Ovsyannikov
Federal State Budgetary Educational Institution of Higher Education “Omsk State Medical University”, Healthcare Ministry of Russia
Russian Federation
Competing Interests:
Russian Federation
Nikolay V. Ovsyannikov - Doctor of Medicine, Associate Professor, Head of Department of Internal Diseases Propedeutics.
Ul. Leninа 12, Omsk, 644099; tel.: (3812) 73-33-37
Competing Interests:
The authors declare absence of conflicts of interest
O. A. Bilevich
Federal State Budgetary Educational Institution of Higher Education “Omsk State Medical University”, Healthcare Ministry of Russia
Russian Federation
Competing Interests:
Russian Federation
Olga A. Bilevich - Candidate of Medicine, Assistant Professor, Associate Professor, Department of Internal Diseases Propedeutics.
Ul. Leninа 12, Omsk, 644099; tel.: (3812) 73-33-37
Competing Interests:
The authors declare absence of conflicts of interest
I. A. Ratynskaya
Federal Budgetary State Healthcare Institution “West Siberian Medical Center of the Federal Medical and Biological Agency of Russia”
Russian Federation
Competing Interests:
Russian Federation
Inna A. Ratynskaya - Candidate of Medicine, Deputy Director of Therapy.
Ul. Krasnyy put’ 127, Omsk, 644033; tel.: (3812) 23-45-74
Competing Interests:
The authors declare absence of conflicts of interest
N. A. Cherkashchenko
Federal Budgetary State Healthcare Institution “West Siberian Medical Center of the Federal Medical and Biological Agency of Russia”
Russian Federation
Competing Interests:
Russian Federation
Natalya A. Cherkashchenko - Candidate of Medicine, Head of the Therapeutic Department.
Ul. Krasnyy put’ 127, Omsk, 644033; tel.: (3812) 23-26-79
Competing Interests:
The authors declare absence of conflicts of interest
I. V. Sazhina
Federal Budgetary State Healthcare Institution “West Siberian Medical Center of the Federal Medical and Biological Agency of Russia”
Russian Federation
Competing Interests:
Russian Federation
Irina V. Sazhina - Therapist, Therapeutic Department.
Ul. Krasnyy put’ 127, Omsk, 644033; tel.: (3812) 23-26-79
Competing Interests:
The authors declare absence of conflicts of interest
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Ovsyannikov N.V., Bilevich O.A., Ratynskaya I.A., Cherkashchenko N.A., Sazhina I.V. Tuberous sclerosis with lung involvement. PULMONOLOGIYA. 2023;33(6):849-855. (In Russ.) https://doi.org/10.18093/0869-0189-2023-33-6-849-855
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