Pneumococcal pneumonia in patients over 60 years of age: features of specific humoral immune response
Abstract
Bacteriological examination of sputum was performed, pneumococcal antigen substances and titers of pneumococcus-specific antibodies were determined in blood serum , IgA, IgM, and IgG serum concentrations were studied in 343 pneumonia patients (217 of them over 60). It was found, that pneumococci, both as monoinfection and in microbial associations, are the most frequent cause of pneumonia in elderly patients. The first week of pneumonia is characterized by maximal incidence of pnemococcal antigenemia and minimal serum titers of pneumococcus—specific antibodies. Pneumococcal antigenemia in pneumococcal pneumonia elderly patients has a characteristic manifestation (the 1st and the 3rd weeks of the disease). Titers of pneumococcus—specific antibodies are decreased, due to increased consumption, in pneumococcal antigenemia and pneumonia induced by mixed infection with pneumococcus.
About the Authors
V. E. NonikovRussian Federation
M. N. Zubkov
Russian Federation
E. N. Gugutsidze
Russian Federation
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Review
For citations:
Nonikov V.E., Zubkov M.N., Gugutsidze E.N. Pneumococcal pneumonia in patients over 60 years of age: features of specific humoral immune response. PULMONOLOGIYA. 1991;(1):15-19. (In Russ.)
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