Diffusing lung capacity and gas exchange among the people, affected by irradiation after Chernobyl atomic power station catastrophe
Abstract
Respiratory function of 9 males at the age of 33—43 who participated in Chernobyl katastrophe consequences liquidation was studied. 4 at them suffered from chronic obstructive bronchitis, 4 — from chronic obstructive bronchitis with purulent sputum and 1 — from asthma.
Different ventilatory alterations were found in 4 cases: mild obstruction (1), moderate obstruction (1), mild hyperinflation (1), mild restriction (1). Three variants of mixed ventilatory defects were also observed in other cases: moderate obstructive defect combined with mild hyperinflation — in 2 cases, combination of moderate obstruction and hyperinflation — in 1 case and mild obstruction with moderate hyperinflation in 1 case. Diffusing lung capacity investigation showed that the most frequent type of alterations (6 cases) was an isolated decrease of DLCO/Va ratio without decrease in DLCO.
Gas exchange studies during the exercise test demonstrated a marked decrease of exercise tolerance. In 3 cases the maximal oxygen uptake was less than 50% pred., and in 5 cases this index was 50—70% pred. An increased dead space volume to the tidal volume ratio and the ventilatory equivalent for O2 demonstrated the gas exchange inefficiency and confirmed the results of DLCO measurement.
The results obtained suggest that these patients have a wide spectrum of respiratory function impairment. Atipical pattern of lung diffusing capacity disorders among the majority of patients can be explained by the nature of radionuclide lung damage.
About the Authors
A. G. Chuchalin
НИИ пульмонологии М3 РФ
Russian Federation
Russian Federation
Z. R. Aisanov
НИИ пульмонологии М3 РФ
Russian Federation
Russian Federation
E. N. Kalmanova
НИИ пульмонологии М3 РФ
Russian Federation
Russian Federation
G. M. Saharova
НИИ пульмонологии М3 РФ
Russian Federation
Russian Federation
T. L. Pashkova
НИИ пульмонологии М3 РФ
Russian Federation
Russian Federation
V. Z. Mamyan
НИИ пульмонологии М3 РФ
Russian Federation
Russian Federation
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Review
For citations:
Chuchalin A.G., Aisanov Z.R., Kalmanova E.N., Saharova G.M., Pashkova T.L., Mamyan V.Z. Diffusing lung capacity and gas exchange among the people, affected by irradiation after Chernobyl atomic power station catastrophe. PULMONOLOGIYA. 1993;(4):61-67. (In Russ.)
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