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Results of complex treatment in patients with alveolitis with hem apheresis use (the posterior observation data review)

Abstract

Investigation data of the 2—10 year duration in 147 patients with idiopathic lung fibrosis are presented. 52 of the patients obtained corticosteroid therapy and 5 of the ones were treated with corticosteroids and plasmapheresis and/or lymphocytapheresis. Complex treatment application with hemapheresis allowed to reach the stable remission more frequently than during the pharmacotherapy in patients with exogenous allergic alveolitis, and to decrease markedly the number of protracted disease. The supplement of hem apheresis in patients with this form of the disease despite of medication treatment significantly increased the efficacy of the therapy and in 2/3 of cases allow ed to achieve the stabilization. The corticosteroid dose decrease as a result of hemapheresis allowed to diminish or remove completely side effects of the steroid therapy in 2/3 of cases.

About the Authors

I. E. Stepanian
Центральный НИИ туберкулеза РАМН
Russian Federation


L. V. Ozerova
Центральный НИИ туберкулеза РАМН
Russian Federation


E. I. Shmelev
Центральный НИИ туберкулеза РАМН
Russian Federation


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Review

For citations:


Stepanian I.E., Ozerova L.V., Shmelev E.I. Results of complex treatment in patients with alveolitis with hem apheresis use (the posterior observation data review). PULMONOLOGIYA. 1993;(3):15-19. (In Russ.)

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ISSN 0869-0189 (Print)
ISSN 2541-9617 (Online)