Immunological and biochemical characteristics of pathogenesis of cryptogenic fibrosing alveolitis and sarcoidosis
Abstract
Immunological and biochemical parameters such as: Interleukin 1 and 2 (IL-1, IL-2), prostaglandin E and F2alfa levels, subpopulations of T-lymphocytes, the activity of elastase and collagenase were studied in patients with cryptogenic fibrosing alveolitis and pulmonary sarcoidosis.
It was found that the immunoreactivity of the patients is characterized by high levels of the IL-1 and IL-2 activity and the T-lymphocyte subpopulation disbalance. High levels of elastase and collagenase in bronchoalveolar fluid in these patients were detected.
About the Authors
T. P. SesRussian Federation
I. V. Pochodsey
Russian Federation
A. G. Bulychev
Russian Federation
E. A. Leonteva
Russian Federation
References
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Review
For citations:
Ses T.P., Pochodsey I.V., Bulychev A.G., Leonteva E.A. Immunological and biochemical characteristics of pathogenesis of cryptogenic fibrosing alveolitis and sarcoidosis. PULMONOLOGIYA. 1993;(2):83-86. (In Russ.)