The importance of nongase exchangable lung function impairments in the pathology development

Abstract

The variance of facts testifying about nongase exchangable functions of lungs (NGEFL) points to the nessessity of thier systematization. The scheme taking in consideration functions of the lung endogenous filter that controls in general the level of urgent and high active compounds of blood, the exogenous obstacle protecting from harmfull influences of environments (pollutants, bacterial and virual agents, e. s.), lung surfactant and the conditioning lung function was present. That functions are connected with the gase exchange, the hemodynamics of small circle of blood circulation, and the excretional lung function.

Considerable impairments of the endogenous filter and lung surfactant were observed during extremal situations (the schock lung, pulmonary oedema), the less expressed ones were observed during obstructive pulmonary diseases (bronchial asthma, chronic • obstructive bronchitis).

Inflammational and destructive processes located in the airways (chronic nonobstructive bronchitis, bronchoectasia, cystic fybrosis et al.) with hypersecretion are followed by most expressed impairments of the exogenous obstacle.

The opinion concerning the nessessity of the detail study of some NGEFL features and perspectives of new metabolic choises in pulmonary patients treatment was expressed.