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Effectiveness of Russian inhaled corticosteroid beclomethasone in bronchial asthma patients

https://doi.org/10.18093/0869-0189-2011-0-4-80-86

Abstract

Summary. Results of efficacy and safety trial of Russian inhaled beclomethasone dipropionate BeclospirR in mild to moderate asthma have been shown in the article. The study involved 60 patients with asthma. During 3 months, clinical efficacy of BeclospirR was compared to that of another preparation of beclomethasone Beclasone Eco using the following common criteria:

• clinical symptoms of asthma (patients' dairies);

• daily need in short-acting bronchodilators;

• peak flow rate;

• level of asthma control;

• spirometric parameters (FEV1 before and after inhalation of salbutamol);

• safety of treatment with BeclospirR.

The results demonstrated that BeclospirR was not inferior to Beclasone Eco. Moreover, BeclospirR in the daily dose of 1 000 μg had certain advantages against Beclasone Eco.

About the Authors

E. I. Shmelev
Центральный НИИ туберкулеза РАМН
Russian Federation


A. F. Abubikirov
Центральный НИИ туберкулеза РАМН
Russian Federation


N. M. Shmeleva
Центральный НИИ туберкулеза РАМН
Russian Federation


M. M. Ilkovich
НИИ пульмонологии ГОУ ВПО "Санкт-Петербургский государственный медицинский университет им. акад. И.П.Павлова"
Russian Federation


N. A. Kuzubova
НИИ пульмонологии ГОУ ВПО "Санкт-Петербургский государственный медицинский университет им. акад. И.П.Павлова"
Russian Federation


References

1. Чучалин А.Г. (ред.). Глобальная стратегия лечения и профилактики бронхиальной астмы (пересмотр 2007 г.). М.: Атмосфера; 2008.

2. Шмелев Е.И. Различия в диагностике и лечении бронхиальной астмы и хронической обструктивной болезни легких. Consilium medicum, 2002; 4 (9): 492–497.

3. Montuschi P., Pagliari G., Fuso L. Pharmacotherapy of asthma: Regular treatment or on demand? Ther. Adv. Resp. Dis. 2009; 3 (4):175–191.

4. Kelly H.W. Comparison of Inhaled Corticosteroids: an update. Ann. Pharmacother. 2009; 43 (3): 519–527.


Review

For citations:


Shmelev E.I., Abubikirov A.F., Shmeleva N.M., Ilkovich M.M., Kuzubova N.A. Effectiveness of Russian inhaled corticosteroid beclomethasone in bronchial asthma patients. PULMONOLOGIYA. 2011;(4):80-86. https://doi.org/10.18093/0869-0189-2011-0-4-80-86

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ISSN 0869-0189 (Print)
ISSN 2541-9617 (Online)