Systemic and regional extracorporeal immunocorrection during therapy of lung suppurative diseases

Abstract

Systemic and regional extracorporal immunocorrection was used in complex treatment of 36 patients with acute lung suppuration. The method consisted of blood perfusion operation — leukocytapheresis with splenoplasmoperfusion with following fiberscope importation of cryopreserved autologic leukocytes into the pulmonary destruction focuses. Lung-pleural suppuration with the tendency to chronization of the process and with the drainaged focus, the tendency to intrapulmonary infection generalization are the indication for this procedure. Blood perfusion operation may be performed after the onset of the catabolic phase of lung suppuration only.

The results showed that blood perfusion operations and following infusion of the autoleukocytes into the infection focuses lead to optimization of both systemic and regional immune reaction and to the more quick focus destruction healing.