Influence of medium osmolality on morphofunctional state of blood neutrophiles in cystic fibrosis
Abstract
The effects of different osmolality levels on functional activity and morphometrical parameters of blood neutrophyles in cystic fibrosis were observed in this study. Functional activity of neutrophyles was estimated on the basis of their ability to produce reactive oxygen species (ROS) (respiratory burst reaction).
There were found some nonsignificant morphometrical changes of neutrophyles under isoosmotic condition, hypoosmotic swelling and hyperosmotic shrinking. Modification of functional neutrophyle activity to form the respiratory burst reaction and dependency of this reaction on osmolality were not revealed.
About the Authors
N. V. Kuchkina
НИИ пульмонологии М3 РФ
Russian Federation
Russian Federation
M. V. Samsonova
НИИ пульмонологии М3 РФ
Russian Federation
Russian Federation
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Review
For citations:
Kuchkina N.V., Samsonova M.V. Influence of medium osmolality on morphofunctional state of blood neutrophiles in cystic fibrosis. PULMONOLOGIYA. 1996;(3):77-79. (In Russ.)
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