Activation of phagocyte nadfh-oxydase by dust participles
Abstract
The effects of “Bazhenov“ chrizotyle-asbestos, quartz DQ12 (international standart) and opsonized zimozan on the main enzyme system of “respiratory burst“– NADPH-oxydase – were analyzed in this study. It was found that all these stimulators evoke direct activation of NADFH-oxydase in peritoneal phagocytes and human blood leucocytes. In spite of some diminished enzyme activity under influence of dust participles compared with zimozan influence, asbestos promotes irreversible enzyme activation leading to axcessive generation of reactive oxygen species in the organism.
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Review
For citations:
Sohodajeva S.K. Activation of phagocyte nadfh-oxydase by dust participles. PULMONOLOGIYA. 1996;(3):65-66. (In Russ.)
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