The absorbing and fermenting activity of phagocytic cells in chronic obstructive bronchitis
Abstract
We studied the phagocytic activity of alveolar macrophages and neutrophils in the peripheric blood and bronchoalveolar lavage fluid (BALF) in 37 patients affected with chronic obstructive bronchitis (COB) and healthy persons to determine the activity of elastase and collagenase in BALF cells and their supernate.
The peripheric blood of COB patients revealed normal neutrophilic and monocytic phagocytosis, while the monocytes of complementary pulmonary emphysematous patients revealed an increased absorbing activity.
BALF demonstrated an acute depression of alveolar macrophagal phagocytosis, which a remission of the inflammatory process raised close to normal only with persons not affected with pulmonary emphysema. COB patients revealed increased activities of elastase and collagenase both in an acute inflammatory process and during remissions. COB patients not affected with pulmonary emphysema displayed the greatest activity increase of elastase.
About the Authors
O. A. SukhovskayaRussian Federation
I. V. Pokhodzei
Russian Federation
N. I. Alexandrova
Russian Federation
A. G. Bulychev
Russian Federation
Ye. A. Leontieva
Russian Federation
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Review
For citations:
Sukhovskaya O.A., Pokhodzei I.V., Alexandrova N.I., Bulychev A.G., Leontieva Ye.A. The absorbing and fermenting activity of phagocytic cells in chronic obstructive bronchitis. PULMONOLOGIYA. 1997;(4):55-58. (In Russ.)