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Assessment of the effectiveness of medical rehabilitation after COVID-19 based on the functional capacity of the cardiovascular and respiratory systems

https://doi.org/10.18093/0869-0189-2021-31-6-710-717

Abstract

Aim. To assess the effectiveness of medical rehabilitation after pneumonia associated with the novel coronavirus infection (COVID-19), based on the study of functional capacity of the cardiovascular system and the external respiratory system.

Methods. The study included 70 patients who had COVID-19 pneumonia and underwent a medical rehabilitation program from September to December 2020. Before being included in the rehabilitation program, all patients underwent pulmonary function tests (PFT), including an assessment of the lungs diffusion capacity, cardiopulmonary exercise testing, multispiral computed tomography (MSCT) of the chest, echocardiography, an evaluation of the quality of life according to the SF-36 questionnaire and the severity of shortness of breath on the mMRC scale. The effectiveness of rehabilitation was evaluated against the changes in PFT parameters, exercise tolerance, and quality of life.

Results. At the enrollment, 46% of patients retained lung tissue lesions shown by MSCT and accompanied by a decrease in the lung diffusion capacity (67 (55 - 79%) of predicted value), dyspnea of 1.6 (1.0 - 3.0) points according to mMRC scale, moderate level of exercise tolerance and quality of life. Complex cardiopulmonary rehabilitation for 12 - 14 days in a specialized hospital led to a significant improvement in the parameters of pulmonary gas exchange and ventilation, peak oxygen consumption, and an increase in the reserve capacity of the cardiorespiratory system. The factors limiting the improvement of pulmonary gas exchange were the older age of the patients and the increased pressure in the pulmonary artery system. The positive influence of rehabilitation on both the physical and psycho-emotional components of the quality of life was noted.

Conclusion. Complex cardiopulmonary rehabilitation with the assessment of changes in the oxygen metabolism parameters and functional capacity of the cardiovascular and respiratory systems has shown to be safe and highly effective in the studied group of patients who have had COVID-19 pneumonia.

About the Authors

Oksana V. Kamenskaya
Federal State Budgetary Institution National Medical Research Center named after Academician E.N.Meshalkin, Ministry of Health of the Russian Federation
Russian Federation

Oksana V. Kamenskaya - Doctor of Medicine, Head of Laboratory of clinical physiology, Department of Anesthesiology and Intensive Care.

Ul. Rechkunovskaya 15, Novosibirsk, 630055; tel.: (383) 347-60-66


Competing Interests:

no



Irina Yu. Loginova
Federal State Budgetary Institution National Medical Research Center named after Academician E.N.Meshalkin, Ministry of Health of the Russian Federation
Russian Federation

Irina Yu. Loginova - Candidate of Biology, Senior Researcher, Laboratory of clinical physiology, Department ofAnesthesiology and Intensive Care.

Ul. Rechkunovskaya 15, Novosibirsk, 630055; tel.: (383) 347-60-66


Competing Interests:

no



Asya S. Klinkova
Federal State Budgetary Institution National Medical Research Center named after Academician E.N. Meshalkin, Ministry of Health of the Russian Federation
Russian Federation

Candidate of Medicine, Researcher, Laboratory of clinical physiology, Department of Anesthesiology and Intensive Care.

Ul. Rechkunovskaya 15, Novosibirsk, 630055; tel.: (383) 347-60-66


Competing Interests:

no



Alexander M. Chernyavsky
Federal State Budgetary Institution National Medical Research Center named after Academician E.N. Meshalkin, Ministry of Health of the Russian Federation
Russian Federation

Doctor of Medicine, Professor, Director.

Ul. Rechkunovskaya 15, Novosibirsk, 630055; tel.: (383) 347-60-40


Competing Interests:

no



Tatiana A. Bergen
Federal State Budgetary Institution National Medical Research Center named after Academician E.N. Meshalkin, Ministry of Health of the Russian Federation
Russian Federation

Candidate of Medicine, Head of the Department of radiation and instrumental diagnostics.

Ul. Rechkunovskaya 15, Novosibirsk, 630055; tel.: (383) 347-60-66


Competing Interests:

no



Alexandra R. Tarkova
Federal State Budgetary Institution National Medical Research Center named after Academician E.N. Meshalkin, Ministry of Health of the Russian Federation
Russian Federation

Candidate of Medicine, Researcher of the Department of radiation and instrumental diagnostics.

Ul. Rechkunovskaya 15, Novosibirsk, 630055; tel.: (383) 347-60-66


Competing Interests:

no



Oleg V. Grishin
Federal State Budgetary Scientific Institution Federal Research Center for Fundamental and Translational Medicine
Russian Federation

Doctor of Medicine, Leading Researcher.

Ul. Timakova 2, Novosibirsk, 630117; tel.: (913) 018-78-84


Competing Interests:

no



Michail I. Voevoda
Federal State Budgetary Scientific Institution Federal Research Center for Fundamental and Translational Medicine
Russian Federation

Professor, Academician of Russian Academy of Sciences, Director.

Ul. Timakova 2, Novosibirsk, 630117; tel.: (383) 335-97-74


Competing Interests:

no



Vladimir V. Lomivorotov
Federal State Budgetary Institution National Medical Research Center named after Academician E.N.Meshalkin, Ministry of Health of the Russian Federation
Russian Federation

Doctor of Medicine, Professor, Corresponding Member of Russian Academy of Sciences, Head of the Department of Anesthesiology and Intensive Care.

Ul. Rechkunovskaya 15, Novosibirsk, 630055; tel.: (383) 347-60-66


Competing Interests:

no



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Review

For citations:


Kamenskaya O.V., Loginova I.Yu., Klinkova A.S., Chernyavsky A.M., Bergen T.A., Tarkova A.R., Grishin O.V., Voevoda M.I., Lomivorotov V.V. Assessment of the effectiveness of medical rehabilitation after COVID-19 based on the functional capacity of the cardiovascular and respiratory systems. PULMONOLOGIYA. 2021;31(6):710-717. (In Russ.) https://doi.org/10.18093/0869-0189-2021-31-6-710-717

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ISSN 0869-0189 (Print)
ISSN 2541-9617 (Online)