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Effectivity of diucifon treatm ent of chronic obstructive pulmonary diseases with chronic lympholeucotic patients

Abstract

The immunomodulating effects of diucifon were studied on 29 chronic lympholeucotic patients at acute stages of chronic obstructive pulmonary diseases, with results compared to tests of 27 patients who were not receiving immunocorrective medication at acute COPD stages accompanied by CLL. Immunotherapy was combined with cytoxan, chlorambucil and prednisolone chemotherapy on universally accepted hematological patterns, and with permanently monitored clinical symptoms, expectoration time according to the amount of inhaled inulin excretion, and tussal clearance, studied by tussography for immunographic characteristics I and II.
Diucifon treatment removed COPD symptoms sooner than with controls. Same about inhaled inulin excretion, and numerical reduction of general and maximum tussal beats. The number of T and В lymphocytes remained unchanged, against an improved helper/suppressor ratio and a tangible im provement of phagocytic characteristics.

About the Authors

V. M. Provotorov
Кафедра факультетской терапии и кафедра клинической фармакологии Воронежской государственной медицинской академии им. Н.Н. Бурденко
Russian Federation


Y. N. Chernov
Кафедра факультетской терапии и кафедра клинической фармакологии Воронежской государственной медицинской академии им. Н.Н. Бурденко
Russian Federation


A. Y. Kazabtsov
Кафедра факультетской терапии и кафедра клинической фармакологии Воронежской государственной медицинской академии им. Н.Н. Бурденко
Russian Federation


L. V. Popova
Кафедра факультетской терапии и кафедра клинической фармакологии Воронежской государственной медицинской академии им. Н.Н. Бурденко
Russian Federation


References

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Review

For citations:


Provotorov V.M., Chernov Y.N., Kazabtsov A.Y., Popova L.V. Effectivity of diucifon treatm ent of chronic obstructive pulmonary diseases with chronic lympholeucotic patients. PULMONOLOGIYA. 1998;(1):24-28. (In Russ.)

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ISSN 0869-0189 (Print)
ISSN 2541-9617 (Online)