Медикаментозные средства предотвращения и минимизации лучевых повреждений легких


https://doi.org/10.18093/0869-0189-2013-0-6-85-91

Полный текст:


Аннотация

Медикаментозные средства предотвращения и минимизации лучевых повреждений легких


Об авторах

М. Г. Сычева
ГБУ "Московский научно-практический центр медицинской реабилитации, восстановительной и спортивной медицины" Департамента здравоохранения Москвы
Россия

к. м. н., ст. научный сотрудник отдела реабилитации больных с заболеваниями бронхолегочной системы 

107120, Москва, Земляной Вал, 53. Тел.: (916) 974-68-63.



Т. И. Грушина
ГБУ "Московский научно-практический центр медицинской реабилитации, восстановительной и спортивной медицины" Департамента здравоохранения Москвы
Россия

д. м. н., руководитель отдела медицинской реабилитации онкологических больных

107120, Москва, Земляной Вал, 53. Тел.: (916) 774-19-39.



Список литературы

1. Ghafoori P., Marks L.B., Vujaskovic Z., Kelsey C.R. Radiation-induced lung injury. Assessment, management and prevention. Oncology 2008; 22 (1): 37–47.

2. Graves P.R., Siddiqui F., Anscher M.S., Movsas B. Radiation pulmonary toxicity: from mechanisms to management. Semin. Radiat. Oncol. 2010; 20 (3): 201–217.

3. Westbury C.B., Yarnold J.R. Radiation fibrosis – current clinical and therapeutic perspectives. Clin. Oncol. (Roy. Coll. Radiol.) 2012; 24 (10): 657–672.

4. Medhora M., Gao F., Jacobs E. R., Moulder J. E. Radiation damage to the lung: Mitigation by angiotensin-converting enzyme (ACE) inhibitors. Respirology 2012; 17 (1): 66–71.

5. Citrin D., Cotrim A.P., Hyodo F. et al. Radioprotectors and mitigators of radiation-induced normal tissue injury. Oncologist 2010; 15: 360–371.

6. Patel V.N., Gupta S., Shareef M.M., Ahmed M.M. Contemporary radiation countermeasures. Defence Sci. J. 2011; 61 (2): 138–145.

7. Movsas B., Vikram B., Hauer-Jensen M. et al. Decreasing the adverse effects of cancer therapy: National Cancer Institute Guidance for the Clinical Development of Radiation Injury Mitigators. Clin. Cancer Res. 2011; 17 (2): 222–228.

8. Васин М.В. Классификация противолучевых средств как отражение современного состояния и перспективы развития радиационной фармакологии. Радиационная биология. Радиоэкология 2013; 53 (5): 459–467.

9. Стюарт Ф.А., Аклеев А.В., Хауэр-Дженсен М. и др. Отчет МКРЗ по тканевым реакциям, ранним и отдаленным эффектам в нормальных тканях и органах – пороговые дозы для тканевых реакций в контексте радиационной защиты (Труды МКРЗ; публикация 118): Пер. с англ. Под ред. А.В.Аклеева, М.Ф.Киселева. Челябинск: Книга 2012.

10. Antonadou D., Coliarakis N., Synodinou M. et al. Randomized phase III trial of radiation treatment / amifostine in patients with advanced-stage lung cancer. Int. J. Radiat. Oncol. Biol. Phys. 2001; 51: 915–922.

11. Antonadou D., Petridis A., Synodinou M. et al. Amifostine reduces radiochemotherapy-induced toxicities in patients with locally advanced non-small cell lung cancer. Semin. Oncol. 2003; 30 (6, Suppl. 18): 2–9.

12. CTEP Common Toxicity Criteria, Version 2.0 DCTD, NCI, NIH, DHHS, March 1998: 24; app IV: 32.

13. Komaki R., Lee J.S., Kaplan B. et al. Randomized phase III study of chemoradiation with or without amifostine for patients with favorable performance status inoperable stage II–III non-small cell lung cancer: Preliminary results. Semin. Radiat. Oncol. 2002; 12 (Suppl. 1): 46–49.

14. Marks L.B., Yu X., Vujaskovic Z. Radiation-induced lung injury. Semin. Radiat. Oncol. 2003; 13: 333–345.

15. Tsoutsou P.G., Koukourarakis M.I. Radiation pneumonitis and fibrosis: mechanism underlying its pathogenesis and implications for future researche. Int. J. Radiat. Oncol. Biol. Phys. 2006; 66 (5): 1281–1293.

16. Movsas B., Scott C., Langer C. et al. Randomized trial of amifostine in locally advanced non-small-cell lung cancer patients receiving chemotherapy and hyperfractionated radiation: Radiation Therapy Oncology Group trial 98–01. J. Clin. Oncol. 2005; 23: 2145–2154.

17. Ozturk B., Egehan I., Atavci S., Kitapci M. Pentoxifylline in prevention of radiation-induced lung toxicity in patients with breast and lung cancer: a double-blind randomized trial. Int. J. Radiat. Oncol. Biol. Phys. 2004; 58: 213–219.

18. Delanian S., Porcher R., Balla-Mekias S., Lefaix J.-L. Randomized, placebo-controlled trial of combined pentoxifillin and tocopherol for regression of superficial radiationinduced fibrosis. J. Clin. Oncol. 2003; 21 (13): 2545–2550.

19. Jacobson G., Bhatia S., Smith B.J., Button A.M. Randomized trial of Pentoxifylline and Vitamin E vs standard follow-up after breast irradiation to prevent breast fibrosis, evaluated by tissue compliance meter. Int. J. Radiat. Oncol. Biol. Phys. 2013; 85 (3): 604–608.

20. Moulder J.E., Cohen E.P. Future strategies for mitigation and treatment of chronic radiation-induced normal tissue injury. Semin. Radiat. Oncol. 2007; 17: 141–148.

21. Molteni A., Moulder J.E., Cohen E.F. et al. Control of radiation-induced pneumopathy and lung fibrosis by angiotensin-converting enzyme inhibitors and an angiotensin II type 1 receptor blocker. Int. J. Radiat. Biol. 2000; 76 (4): 523–532

22. Molteni A., Wolfe L.F., Ward W.F. et al. Effect of an angiotensin II receptor blocker and two angiotensin converting enzyme inhibitors on transforming growth factor-beta (TGF-β) and alpha-actomyosin (alpha SMA), important mediators of radiation-induced pneumopathy and lung fibrosis. Curr. Pharm. Des. 2007; 13: 1307–1316.

23. Ghosh S.N., Zhang R., Fish B.L. et al. Renin-Angiotensin system suppression mitigates experimental radiation pneumonitis. Int. J. Radiat. Oncol. Biol. Phys. 2009; 75 (5): 1528–1536.

24. Medhora M., Gao F., Fish B.L. et al. Dose-modifying factor for captopril for mitigation of radiation injury to normal lung. J. Radiat. Res. 2012; 53 (4): 633–640.

25. Molthen R.C., Wu Q., Fish B.L. et al. Mitigation of radiation induced pulmonary vascular injury by delayed treatment with captopril. Respirology 2012; 17 (8): 1261–1268. doi: 10.1111/j.1440-1843.2012.02247.x.

26. Williams J.P., Jackson I.L., Shah J.R. et al. Animal models and medical countermeasures development for radiationinduced lung damage: Report from an NIAID Workshop. Radiat. Res. 2012; 177: e0025–e0039. doi: 10.1667/RROL04.1

27. Kharofa J., Cohen E.P., Tomic R. et al. Decreased risk of radiation pneumonitis with incidental concurrent use of angiotensin-converting enzyme inhibitors and thoracic radiation therapy. Int. J. Radiat. Oncol. Biol. Phys. 2012; 84 (1): 238–243.

28. Williams J.P, Johnston C.J., Finkelstein J.N. Treatment for radiation-induced pulmonary late effects: Spoiled for choice or looking in the wrong direction? Curr. Drug Targets 2010; 11 (11): 1386–1394.

29. Sun X.F., Wang L.L., Wang J.K. et al. Effects of simvastatin on lung injury induced by ischaemia-reperfusion of the hind limbs in rats. J. Int. Med Res. 2007; 35: 523–533.

30. Yao H.W., Mao L.G., Zhu J.P. Protective effects of pravastatin in murine lipopolysaccharide-induced acute lung injury. Clin. Exp. Pharmacol. Physiol. 2006; 33: 793–797.

31. Xia D.H., Xi L., Xy C. et al. The protective effects of ambroxol on radiation lung injury and influence on production of transforming growth factor beta1 and tumor necrosis factor alpha. Med. Oncol. 2010; 27 (3): 697–701. doi:10.1007/s12032-009-9271-3.

32. Demedts M., Behr J., Buhl R. et al. High-dose Acetylcysteine in idiopathic pulmonary fibrosis. N. Engl. J. Med. 2005; 353: 2229–2242.

33. Noble P.W., Albera C., Bradford W.Z. et al. Pirfenidone in patients with idiopathic pulmonary fibrosis (CAPACITY): two randomised trials. Lancet 2011; 377 (9779): 1760–1769.

34. Bargagli E., Galeazzi M., Bellisai F. et al. Infliximab treatment in a patient with systemic sclerosis associated with lung fibrosis and pulmonary hypertension. Respir. Intern. Rev. Thorac. Dis. 2008; 75 (3): 346–349.

35. Staroslawska E., Czarnocki K. J., Koziol-Montewka M. et al. Effect of infliximab on the levels of TNF-α and TGF-β in the whole blood cultures of irradiated patients. Folia Histochem. Cytobiol. 2008; 46 (3): 291–297.

36. Hunter N.R., Valdecanas D., Liao Z. et al. Mitigation and treatment of radiation-induced thoracic injury with a cyclooxygenase-2 inhibitor, celecoxib. Int. J. Radiat. Oncol. Biol. Phys. 2013; 85 (2): 472–476. doi: 10.1016/j.ijrobp.2012. 04.025.

37. Komaki R., Wei X., Allen P.K. et al. Phase I study of Celecoxib with concurrent Irinotecan, Cisplatin, and radiation therapy for patients with unresectable locally advanced non-small cell lung cancer. Front. Oncol. 2011; 1: 52. Published online 2011 December 13.

38. Epperly M., Bray J., Kraeger S. et al. Prevention of late effects of irradiation lung damage by manganese superoxide dismutase gene therapy. Gene Ther. 1998; 5: 196–208.

39. Lefaix J.-L., Delanian S., Leplat J.J. et al. Successful treatment of radiation-induced fibrosis using Cu/Zn-SOD and Mn-SOD: An experimental study. Int. J. Radiat. Oncol. Biol. Phys. 1996; 35: 305–312.

40. Kang S.K., Rabbani Z.N., Folz R.J. et al. Overexpression of extracellular superoxide dismutase protects mice from radiation-induced lung injury. Int. J. Radiat. Biol. Oncol. Phys. 2003; 47: 1056–1066.

41. Rabbani Z.N., Anscher M.S., Folz R.J. et al. Overexpression of extracellular superoxide dismutase reduces acute radiation induced lung toxicity. BMC Cancer 2005; 5: 59. doi:10.1186/1471-2407-5-59.

42. Vujaskovic Z., Batinic-Haberle I., Rabbani Z.N. et al. A small molecular weight catalytic metalloporphyrin antioxidant with superoxide dismutase (SOD) mimetic properties protects lungs from radiation-induced injury. Free Radic. Biol. Med. 2002; 33: 857–863.

43. Mahmood J., Jelveh S., Calveley V. et al. Mitigation of radiation-induced lung injury by genistein and EUK-207. Int. J. Radiat. Biol. 2011; 87 (8): 889–901.

44. Mahmood J., Jelveh S., Zaidi A. et al. Mitigation of radiation-induced lung injury with EUK-207 and genistein: effects in adolescent rats. Radiat. Res. 2013; 179 (2): 125–134.

45. Kunwar A., Jain V.K., Priyadarsini K.I., Haston C.K. A Selenocysteine Derivative therapy affects radiation-induced pneumonitis in the mouse. Am. J. Respir. Cell. Mol. Biol. 2013; 49 (4): 654–661.

46. Драчев И.С., Легеза В.И., Турлаков Ю.С. Перспективы применения соединений селена в качестве радиопротекторов. Радиац. биол. радиоэкол. 2013; 53 (5): 475–480.

47. Yazici G., Yildis F., Iskit A. et al. The effect of vitamin D prophylaxis on radiation induced pulmonary damage. J. Radiat. Res. 2011; 52 (5): 616–621.

48. Lee J.C, Kinniry P.A., Arguiri E. et al. Dietary curcumin increases antioxidant defenses in lung, ameliorates radiation-induced pulmonary fibrosis, and improves survival in mice. Radiat. Res. 2010; 173 (5): 590–601.

49. Cho Y.J., Yi Ch.O., Jeon B.T. et al. Curcumin attenuates radiation-induced inflammation and fibrosis in rat lungs. Korean J. Physiol. Pharmacol. 2013; 17 (4): 267–274. English. Published online 2013 July 30.

50. Liu Y., Yu H., Zhang C. Protective effects of berberine on radiation-induced lung injury via intercellular adhesion molecular-1 and transforming growth factor-beta-1 in patients with lung cancer. Eur. J. Cancer 2008; 44: 2425–2432.

51. Calveley V.L., Jelveh S., Langan A. et al. Genistein can mitigate the effect of radiation on rat lung tissue. Radiat. Res. 2010; 173 (5): 602–611.

52. Xavier S., Piek E., Fujii M. et al. Amelioration of radiationinduced fibrosis: inhibition of transforming growth factorbeta signalling by halofuginone. J. Biol. Chem. 2004; 279 (15): 15167–15176.

53. Liu H., Xue J.X., Li X. et al. Quercetin liposomes protect against radiation-induced pulmonary injury in a murine model. Oncol. Lett. 2013; 6 (2): 453–459.

54. Robb W.B., Condron C., Moriarty M. et al. Taurine attenuates radiation-induced lung fibrosis in C57/Bl6 fibrosis prone mice. Irish J. Med. Sci. 2010; 179 (1): 99–105.

55. Brizel D.M. Pharmacologic approaches to radiation protection. J. Clin. Oncol. 2007; 25 (26): 4084–4089.

56. Haiping Z., Takayama K., Uchino J. et al. Prevention of radiation-induced pneumonitis by recombinant adenovirusmediated transferring of soluble TGF-beta type II receptor gene. Cancer Gene Ther. 2006; 13 (9): 864–872.

57. Katoh H., Ishikawa H., Hasegava M. et al. Protective effect of urinary trypsin inhibitor on the development of radiationinduced lung fibrosis in mice. J. Radiat. Res. 2010; 51 (3): 325–332.

58. Shimbo T., Inomata T., Takahashi M.et al. Effects of sivelestat sodium hydrate on the reduction of radiation pneumonitis. Int. J. Mol. Med. 2007; 20 (6): 817–822.

59. Fox J., Haston C.K. CXC receptor 1 and 2 and neutrophil elastase inhibitors alter radiation-induced lung disease in the mouse. Int. J. Radiat. Oncol. Biol. Phys. 2013; 85 (1): 215–222. doi: 10.1016/j.ijrobp.2012.02.024.

60. Li M., Abdollahi A., Grone H.L. et al. Late treatment with imatinib mesylate ameliorates radiation-induced lung fibrosis in a mouse model. Radiat. Oncol. 2009; 4: 66. Published online 2009 December 21.


Дополнительные файлы

Для цитирования: Сычева М.Г., Грушина Т.И. Медикаментозные средства предотвращения и минимизации лучевых повреждений легких.  Пульмонология. 2013;(6):85-91. https://doi.org/10.18093/0869-0189-2013-0-6-85-91

For citation: Sycheva M.G., Grushina T.I. Drug therapy to prevent and diminish radiation injury of the lungs. Russian Pulmonology. 2013;(6):85-91. (In Russ.) https://doi.org/10.18093/0869-0189-2013-0-6-85-91

Просмотров: 483

Обратные ссылки

  • Обратные ссылки не определены.


ISSN 0869-0189 (Print)
ISSN 2541-9617 (Online)