Follow-up pulmonary function of COVID-19 patients 4 months after hospital discharge
Olga I. Savushkina,
Alexander V. Cherniak,
Evgeniy V. Kryukov,
Nataliya A. Aseeva,
Andrey A. Zaytsev https://doi.org/10.18093/0869-0189-2021-31-5-580-587
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Abstract
The end of the acute period of COVID-19 does not mean complete recovery. Observation of patients in the post-COVID-19 period showed that a significant number of people experience shortness of breath, fatigue, muscle weakness, sleep disorders, cough, palpitations, so the term post-COVID-19 syndrome was coined. The examination to identify the causes of complaints of COVID-19 convalescents should include lung function assessment.
The aim of the study was to assess the dynamics of lung function 4 months after hospitalization for COVID-19.
Methods. 31 patients (26 males, the median age was 49 years) underwent traditional pulmonary function tests (PFTs) (spirometry, body plethysmography, test of diffusing lung capacity) and impulse oscillometry (IOS). Results. During the 1st visit, the average PFTs and IOS parameters were within the normal range in the whole group, apart from the diffusing lung capacity (DLCO), which was reduced mildly (on the border with moderate) in 77% of patients. During the 2nd visit, which was conducted on average 102 days after the 1st one, 58% of patients demonstrated abnormal lung diffusion capacity. The second assessment revealed a statistically significant increase in the slow and forced vital capacity (VC and FVC), the forced exhalation volume in 1 second (FEV1), total lung capacity (TLC), DLCO, and a decrease in the ratio of FEV1/FVC and the residual lung volume to TLC ratio.
Conclusion. Post-COVID-19 patients show a statistically significant improvement of their lung function 4 months after hospital discharge. A systematic follow-up is essential for such patients to detect lung function abnormalities and correct them.
About the Authors
Olga I. Savushkina
Main Military Clinical Hospital named after academician N.N. Burdenko, Ministry of Defense; Federal State Budgetary Institution ‟Pulmonology Scientific Research Institute”, Federal Medical and Biological Agency
Russian Federation
Competing Interests:
Russian Federation
Olga I. Savushkina, Candidate of Biology, Head of Department of Lung Function Testing; Senior Researcher, Laboratory of Functional and Ultrasound Research Methods
SPIN-code: 2988-8700; Author ID: 964904
Gospital’naya pl. 3, Moscow, 105229;
Orekhovyy bul’var 28, Moscow, 115682
tel.: (499) 263-28-61
Competing Interests:
The authors declared the absence of conflict of interests, which should be reported
Alexander V. Cherniak
Federal State Budgetary Institution ‟Pulmonology Scientific Research Institute”, Federal Medical and Biological Agency
Russian Federation
Competing Interests:
Russian Federation
Alexander V. Cherniak, Candidate of Medicine, Head of the Laboratory of Functional and Ultrasonic Research Methods
SPIN-code: 9328-6440; Author ID: 687383
Orekhovyy bul’var 28, Moscow, 115682
tel.: (495) 395-63-93
Competing Interests:
The authors declared the absence of conflict of interests, which should be reported
Evgeniy V. Kryukov
Federal State Budgetary Military Educational Institution of Higher Education “The S.M. Kirov Military Medical Academy”, Ministry of Defense
Russian Federation
Competing Interests:
Russian Federation
Evgeniy V. Kryukov, Doctor of Medicine, Professor, Corresponding Member of Russian Academy of Sciences, Head
SPIN-code: 3900-3441; Author ID: 879052
ul. Akademika Lebedeva 6, Saint-Petersburg, 194044
tel.: (812) 667-71-18
Competing Interests:
The authors declared the absence of conflict of interests, which should be reported
Nataliya A. Aseeva
Main Military Clinical Hospital named after academician N.N. Burdenko, Ministry of Defense
Russian Federation
Competing Interests:
Russian Federation
Nataliya A. Aseeva, Physician, Department of Respiratory Function Research, Center for Functional Diagnostic Research
Gospital’naya pl. 3, Moscow, 105229
tel.: (499) 263-38-61
Competing Interests:
The authors declared the absence of conflict of interests, which should be reported
Andrey A. Zaytsev
Main Military Clinical Hospital named after academician N.N. Burdenko, Ministry of Defense
Russian Federation
Competing Interests:
Russian Federation
Andrey A. Zaytsev, Doctor of Medicine, Professor, Chief Pulmonologist
SPIN-code: 6549-5154; Author ID: 217005
Gospital’naya pl. 3, Moscow, 105229
tel.: (499) 263-29-00
Competing Interests:
The authors declared the absence of conflict of interests, which should be reported
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For citations:
Savushkina O.I., Cherniak A.V., Kryukov E.V., Aseeva N.A., Zaytsev A.A. Follow-up pulmonary function of COVID-19 patients 4 months after hospital discharge. PULMONOLOGIYA. 2021;31(5):580-586. (In Russ.) https://doi.org/10.18093/0869-0189-2021-31-5-580-587
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ISSN 2541-9617 (Online)
ISSN 2541-9617 (Online)
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