The upper respiratory tract microbiome and its role in human health: biotopes and variability
https://doi.org/10.18093/0869-0189-2022-32-5-745-754
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Abstract
Human respiratory tract is a complex system with a specific microbiological profile. Until recently, researchers were mostly interested in lung microbial communities associated with acute and chronic infections. The upper respiratory tract microbiota has gained attention during COVID-19 pandemic as it was proposed to be one of the factors affecting the course and the outcome of viral infections. The aim. In this review, we summarized the current knowledge about microbial communities in each section of the upper respiratory tract, considering the proposed barrier function of the respiratory microbiome. Conclusion. The facts provided in the first part of this review give a modern perspective on the structure of microbial communities of each part of the upper respiratory tract and factors that affect their variability.
About the Authors
E. V. Starikova
Federal Research & Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency
Russian Federation
Competing Interests:
Russian Federation
Elizaveta V. Starikova, Researcher, Laboratory of Genomic Research and Computational Biology
ul. Malaya Pirogovskaya 1a, Moscow, 119435
Competing Interests:
The author declares no conflict of interests
Ju. S. Galeeva
Federal Research & Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency
Russian Federation
Competing Interests:
Russian Federation
Yuliya S. Galeeva, Research Assistant at Laboratory of Genomic Research and Computational Biology
ul. Malaya Pirogovskaya 1a, Moscow, 119435
Competing Interests:
The author declares no conflict of interests
E. N. Ilina
Federal Research & Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency
Russian Federation
Competing Interests:
Russian Federation
Elena N. Ilina, Doctor of Biology Science, Professor, Corresponding Member of Russian Academy of Sciences, Head of Laboratory of Genomic Studies and Computational Biology, Deputy Director for Science
ul. Malaya Pirogovskaya 1a, Moscow, 119435
Competing Interests:
The author declares no conflict of interests
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Starikova E.V., Galeeva J.S., Ilina E.N. The upper respiratory tract microbiome and its role in human health: biotopes and variability. PULMONOLOGIYA. 2022;32(5):745-754. (In Russ.) https://doi.org/10.18093/0869-0189-2022-32-5-745-754
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