Роль микробиома верхних дыхательных путей в здоровье человека: биотопы и изменчивость
https://doi.org/10.18093/0869-0189-2022-32-5-745-754
Аннотация
Дыхательные пути (ДП) человека представляют собой сложную систему, обладающую собственным микробным профилем. До недавнего времени основной интерес научного сообщества вызывали микробные сообщества легких, ассоциированные с различными заболеваниями. В период пандемии COVID-19 внимание специалистов сосредоточилось на микробиоте верхних ДП (ВДП), которая, предположительно, является одним из факторов, оказывающих влияние на течение вирусных инфекций. Целью работы явились систематизация и оценка известной к настоящему моменту информации о микробных сообществах каждого из отделов ВДП, однако особое внимание уделено предположительной барьерной функции респираторной микробиоты. Заключение. Приводятся данные, обобщающие известную информацию о микробных сообществах каждого из отделов ВДП и факторах, оказывающих влияние на состав респираторной микробиоты.
Об авторах
Е. В. Старикова
Федеральное государственное бюджетное учреждение «Федеральный научно-клинический центр физико-химической медицины» Федерального медико-биологического агентства
Россия
Конфликт интересов:
Россия
Старикова Елизавета Валентиновна – младший научный сотрудник лаборатории геномных исследований и вычислительной биологии
119435, Москва, ул. Малая Пироговская, 1а
Конфликт интересов:
Автор заявляет об отсутствии конфликта интересов.
Ю. С. Галеева
Федеральное государственное бюджетное учреждение «Федеральный научно-клинический центр физико-химической медицины» Федерального медико-биологического агентства
Россия
Конфликт интересов:
Россия
Галеева Юлия Сергеевна – лаборант-исследователь лаборатории геномных исследований и вычислительной биологии
119435, Москва, ул. Малая Пироговская, 1а
Конфликт интересов:
Автор заявляет об отсутствии конфликта интересов.
Е. Н. Ильина
Федеральное государственное бюджетное учреждение «Федеральный научно-клинический центр физико-химической медицины» Федерального медико-биологического агентства
Россия
Конфликт интересов:
Россия
Ильина Елена Николаевна – доктор биологических наук, профессор, член-корр. Российской академии наук, заведующая лабораторией геномных исследований и вычислительной биологии, заместитель директора по науке
119435, Москва, ул. Малая Пироговская, 1а
Конфликт интересов:
Автор заявляет об отсутствии конфликта интересов.
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Для цитирования:
Старикова Е.В., Галеева Ю.С., Ильина Е.Н. Роль микробиома верхних дыхательных путей в здоровье человека: биотопы и изменчивость. Пульмонология. 2022;32(5):745-754. https://doi.org/10.18093/0869-0189-2022-32-5-745-754
For citation:
Starikova E.V., Galeeva J.S., Ilina E.N. The upper respiratory tract microbiome and its role in human health: biotopes and variability. PULMONOLOGIYA. 2022;32(5):745-754. (In Russ.) https://doi.org/10.18093/0869-0189-2022-32-5-745-754
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