Pathological features of chronic obstructive bronchitis

Abstract

Based on light and electronic microscopic examination of bronchial wall biopsy species the principal pathological features of chronic bronchitis and bronchial asthma were defined. Apart from typical catarrhal changes and the ciliary cell substitution for the goblet cells, the hyperplasia of the latter ones and hypersecretion they were as follows: an occurrence of immune inflammation signs with considerable cell infiltration of the bronchial wall by eosinophilic leukocytes and degranulated mast cells and concentration of active plasma cells. Moreover, there was significant sedimentation of structured fibrin with a character striation inside the bronchi.