Monitoring autonomic activity in asthma
Abstract
The spectral analysis of the heart rate variability was performed to assess the autonomic nervous system activity associated with 49 asthma attacks in 19 asthma patients. The 24-h Holter ECG recordings during 5-min intervals for 2 hours before to 1 hour after each asthma attack were analyzed using the fast Fourier analysis. There were no changes in low and high frequency bands in 73 % of the cases. The high frequency band (0.15-0.40 Hz) reflecting the parasympathetic activity increased 10 to 40 min before the asthma attacks in 27 % of the cases. The low frequency band (0.05-0.15 Hz) reflecting sympathetic activity increased before the asthma attacks finishing in 37 % of the cases that was typically for the nighttime symptoms and the attacks with the previous increase of the parasympathetic activity.
About the Authors
F. I. Belyalov
Иркутский государственный медицинский университет
Russian Federation
Russian Federation
N. S. Lesina
Иркутский государственный медицинский университет
Russian Federation
Russian Federation
References
1. Global strategy for asthma management and prevention NHLBI/ WHO workshop. 1995.
2. Kamath M.V., Ghista D.N., Fallen E.L. et al. Heart rate variability power spectrogram as a potential noninvasive signature of cardiac regulatory system response, mechanisms and disorders. Heart and Vessels 1987; 3: 33-41.
3. Kazuma N., Otsuka K., Matsuoka I., Murata M. Heart rate variability during 24 hours in asthmatic children. Chronobiol. Int. 1997; 14: 597-606.
4. Pagani M.L., Lombardi F Guzzettis S. et al. Power spectral analysis of heartrate and arterial pressure variabilities as an marker of sympathovagal interaction in man and conscious dogs. Circ. Res. 1986; 59: 178-193.
5. Task force of The European Society of Cardiology and The North American Society of Pacing and Electrophysiology. Eur. Heart J. 1996;17:354-381.
6. Jartti T.T., Kaila T.J., Tahvanainen K.U. et at. The acute effects of inhaled salbutamol on the beat-to-beat variability of heart rate and blood pressure assessed by spectral analysis. Brt. J. Clin. Pharmacol. 1997; 43: 421-428.
7. Pagani М., Lucini D., P izzinelli P. et al. Effects of aging and of chronic obstructive pulmonary disease on RR interval variability. J. Auton. Nerv. Syst. 1996; 59: 125-132.
8. Stein P.K., Nelson P., Rottman J.N. et al. Heart rate variability reflects severity of COPD in PiZ alpha 1-antitrypsin deficiency. Chest 1998; 113: 327-333.
9. Ado А.Д., Золотарева P M . Холинергический вариант неинфекционно-аллергической бронхиальной астмы. Клин. мед. 1986;8:47-51.
10. Jartti Т.Т., Tahvanainen K.U., Kaila T.J. et al. Cardiovascular autonomic regulation in asthmatic children evidenced by spectral analysis of heart rate and blood pressure variability. Scand. J. Clin. Lab. Invest. 1996; 56: 545-554.
11. National asthma education and prevention program. Expert panel report 2. Guidelines for the diagnosis and management of asthma. NIH, NHLBI. 1997.
12. Jartti T.T., Kaila T.J., Tahvanainen K.U. et al. Altered cardiovascular autonomic regulation after 2-week inhaled salbutamol treatment in asthmatic children. Eur. J. Pediatr. 1997; 156: 883-888.
Review
For citations:
Belyalov F.I., Lesina N.S. Monitoring autonomic activity in asthma. PULMONOLOGIYA. 2004;(2):46-49. (In Russ.)
Views:
173
Email this article 