Clinical significance of evaluation of 11-5 gene expression in bronchial asthma

1. Bochner В.S., Undem B.J., Lichtenstein L.M. Immunological aspects of allergic asthma. Annu. Rev.. Immunol. 1994; 12: 295-335.

2. Kay A.B., Menzies-Gow A. Eosinophils and interleukin-5: the debate continues. Am. J. Respir. Crit. Care Med. 2003; 167 (12): 1586-1587.

3. Ogawa K., Hashida P., M iyagawa M. et al. Analysis of gene expression in peripheral blood eosinophils from patients with atopic dermatitis and in vitro cytokine-stimulated blood eosinophils. Clin. Exp. Immunol. 2003; 131 (3): 4 3 6-4 45 .

4. Huston D.P. Interleukin-5: a therapeutic target in asthma. Int. J. Immunorehabil. 1997; 7: 7-4

5. . 5. Freidin M.B., Kobyakova O.S., Ogorodova L.M., Puzyrev V.P. Association of polymorphisms in the human IL-4 and IL-5 genes with atopic bronchial asthma and severity of the disease. Comp. Funct. Genom. 2003; 4: 3 4 6-350.

6. Global initiative for asthma. Global strategy for asthma management and prevention, 2002 / /www.ginasthma.com.

7. Popov T.A., Pizzichini M .M ., Pizzichini E. et al. Some technical factors influencing the induction sputum for cells analysis. Clin. Exp. Allergy. 1995; 8: 5 5 9-565.

8. Corrigan C.J. Cytokines (interleukines). In: Kay A.B., ed. Allergy and allergic diseases. Oxford: Blackwell Science; 1997; vol. 1: 3 5 -41 .

9. Огородова Л.М., Кобякова О.С., Петровский Ф.И. и др. Многоцентровое исследование сравнительной эффективности режимов комбинированной терапии у пациентов с тяжелой неконтролируемой бронхиальной астмой. Качеств, клин, практика 2002; 2: 18-26.

10. Humbert М., Corrigan C.J., Kimmitt P. et al. Relationship between IL-4 and IL-5 mRNA expression and disease severity in atopic asthma. Am. J. Respir. Crit. Care Med. 1997; 156 (3): 704-708.

11. Minsall E.M., Schleimer R., Cameron L. et al. Interleukin-5 Expression in the bone marrow of sensitized b a lb / c mice after allergen challenge. Am. J. Respir. Crit. Care Med. 1998; 158 (3): 951-957.

12. Сазонов А .Э ., Петровский Ф.И., Иванчук И.И. и др. Экспрессия HJ1-5 в мокроте больных бронхиальной астмой. Бюл. экспер. биол. 2003; 135 (4): 437-440.

13. Menzies-Gow A., Flood-Page P., Sehmi. R. et al. Anti-lL-5 (mepolizumab) therapy induces bone marrow eosinophil maturational arrest and decreases eosinophil progenitors in the bronchial mucosa of atopic asthmatics. J. Allergy Clin. Immunol. 2003; 111 (4): 714 -719 .

14. Hakonarson H., Maskeri N . t Carter C., Grunste in M .M . Regulation of TH1- and TH2-type cytokine expression and action in atopic asthmatic sensitized airway smooth muscle. J. Clin. Invest. 1999; 103: 1077-1087.

15. Rizzo C.A., Yang R., Greenfeder S. et al. The IL-5 receptor on human bronchus selectively primes for hyperresponsiveness. J. Allergy Clin. Immunol. 2002; 109 (3): 404-409.

16. Salvi S., Semper A., Blomberg A. et al. Interleukin-5 production by hum an airway epithelial cells. Am. J. Respir. Cell. Mol. Biol. 1999; 20: 984-991.