Cavity forms of thoracic sarcoidosis (literature review, clinical and radiological observations)
https://doi.org/10.18093/0869-0189-2020-30-6-831-841
Abstract
Cavity forms of sarcoidosis, which require differential diagnosis with other diseases, manifested by X-ray cavity patterns, polysegmental nodular formations, hilus and mediastinal lymphadenopathy, are extremely rare. The data of the world literature (1973 - 2018) on the studied problem are analyzed, the results of our own clinical and radiological observations of patients (n = 490) with various forms of sarcoidosis are presented. Cavity forms of sarcoidosis were detected in 31 (6.3%) cases — fibrocystic variants in stage IV sarcoidosis (n = 8); sarcoidosis on the background of cystic hypoplasia (n = 7); combined forms of primary cavity sarcoidosis and necrotic sarcoid granulomatosis in 6 (1.2%) patients; a combination of sarcoidosis and fibro-cavernous tuberculosis (n = 5); sarcoidosis with the pattern “reverse halo sign” (n = 5). Examples of our own clinical and radiological observations are presented. The modern methods of multispiral computed tomography have been optimized, the capabilities of the basic post-processing image processing programs have been demonstrated, the use of which significantly increases the sensitivity and specificity of tomographic research.
About the Authors
A. V. Lenshin
Far Eastern Research Center of Physiology and Respiratory Pathology
Russian Federation
Competing Interests: not
Russian Federation
Anatoliy V. Lenshin - Doctor of Medicine, Professor, Leading Researcher, Laboratory of Functional Research of Respiratory System.
Ul. Kalinina 22, Blagoveshchensk, 675000; tel.: (914) 558-19-37
Competing Interests: not
A. V. Il'in
Far Eastern Research Center of Physiology and Respiratory Pathology
Russian Federation
Competing Interests: not
Russian Federation
Andrey V. Il'in - Candidate of Medicine, Senior Researcher, Laboratory of Molecular and Translational Research.
Ul. Kalinina 22, Blagoveshchensk, 675000; tel.: (914) 561-69-52
Competing Interests: not
Yu. M. Perelman
Far Eastern Research Center of Physiology and Respiratory Pathology
Russian Federation
Competing Interests: not
Russian Federation
Yuliy M. Perelman - Doctor of Medicine, Professor, Corresponding Member of Russian Academy of Sciences, Head of Laboratory of Functional Investigations of Respiratory System.
Ul. Kalinina 22, Blagoveshchensk, 675000; tel.: (4162) 77-28-01
Competing Interests: not
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For citations:
Lenshin A.V., Il'in A.V., Perelman Yu.M. Cavity forms of thoracic sarcoidosis (literature review, clinical and radiological observations). PULMONOLOGIYA. 2020;30(6):831-841. (In Russ.) https://doi.org/10.18093/0869-0189-2020-30-6-831-841
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