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PULMONOLOGIYA

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Cytological markers of non-progredient course of respiratory oxalosis

https://doi.org/10.18093/0869-0189-2005-0-6-81-85

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Abstract

Respiratory oxalosis (RO), a special hereditary form of obstructive lung disease accompanied by hyperoxaluria, non-progredient course, absence of allergy and several cytology markers was studied in this comparative prospective study. We have observed 2 groups of non-smoking women (71 patients with RO and 64 patients with asthma accompanied by allergy with progredient course during 5 years). We evaluated the locomotor function of the mononuclear and polynuclear blood phagocytes using the inhibition of lymphocyte migration test as an immunological marker, and the hepatocyte function using AST / ALT ratio as a cytological marker. Their prevalence was the greatest in the 1-st group and constituted 100 % for the immunological marker and 98 % for the cytological one.
We assume that function of the mononuclear phagocytes in RO probably results in the non progredient course of the disease. It relates to congenital high threshold of the immunocompetent cell sensitivity to polyclonal mitogens.

For citations:


Pospekhova G.P., Aleshina L.A., Voronina O.V., Vakharlovsky V.G., Razorenova T.S. Cytological markers of non-progredient course of respiratory oxalosis. PULMONOLOGIYA. 2005;(6):81-85. (In Russ.) https://doi.org/10.18093/0869-0189-2005-0-6-81-85

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ISSN 0869-0189 (Print)
ISSN 2541-9617 (Online)