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Evaluation of efficacy of thiotropium bromide administration to chronic obstructive lung disease patients at Novosibirsk region

https://doi.org/10.18093/0869-0189-2005-0-4-92-96

Abstract

A regional branch programme "Improvement of quality of life of COPD patients" had been developed and adopted at Novosibirsk region. Its content is financial support and organization of COPD treatment using thiotropium bromide.
The study involved 35 COPD patients, 31of them (28 males and 3 females) completed the treatment. The average age of participants was 53.2 ± 3.9 yrs. We assessed severity of clinical signs using a 3-point scale; spirometry parameters, physical tolerability in 6-minute walk test. We also calculated cost of therapy of COPD patients. The follow-up duration was 6 months. Results demonstrated a significant reduction in clinical severity of COPD, improvement in functional capacity during the treatment with Spiriva. The rate of seeking for aid, number of seek days and length of staying in a hospitals decreased. Medical expenses for COPD treatment increased when used Spiriva due to its high cost but with regards to a total expenditure (direct and indirect) the cost-efficacy was 32.7 %.

About the Authors

S. S. Pavlenko
Новосибирская государственная областная клиническая больница; Искитимская центральная районная больница
Russian Federation


N. S. Pavlenko
Новосибирская государственная областная клиническая больница; Искитимская центральная районная больница
Russian Federation


L. M. Kudelya
Новосибирская государственная областная клиническая больница; Искитимская центральная районная больница
Russian Federation


L. Ya. Morozova
Новосибирская государственная областная клиническая больница; Искитимская центральная районная больница
Russian Federation


A. A. Kaigorodov
Новосибирская государственная областная клиническая больница; Искитимская центральная районная больница
Russian Federation


References

1. Глобальная стратегия: диагностика, лечение и профилактика хронической обструктивной болезни легких. Доклад рабочей группы. Краткое изложение. U.S. Department of Health and Human Services. NIH Publication № 2701. April 2001.

2. Авдеев С.Н. Роль тиотропия в терапии больных хронической обструктивной болезнью легких: новые данные (по материалам 14-го конгресса Европейского респираторного общества, Глазго, 2004). Consilium Medicum: 2004; (10): 1–10.

3. Dusser D., Bravo M.L., Iacono P., on Behalf of the MISTRAL Study Group. Tiotropium reduces health resource utilization associated with COPD exacerbations. Eur. Respir. J. 2004; 24 (suppl. 48): 513 s. Поступила 24.08.0


Review

For citations:


Pavlenko S.S., Pavlenko N.S., Kudelya L.M., Morozova L.Ya., Kaigorodov A.A. Evaluation of efficacy of thiotropium bromide administration to chronic obstructive lung disease patients at Novosibirsk region. PULMONOLOGIYA. 2005;(4):92-96. (In Russ.) https://doi.org/10.18093/0869-0189-2005-0-4-92-96

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ISSN 0869-0189 (Print)
ISSN 2541-9617 (Online)