Clinical and functional featuresof respiratory heat exchange and cold airway hyperresponsiveness in patients with bronchial asthma and chronic polypous rhinosinusitis
https://doi.org/10.18093/0869-0189-2008-0-6-59-62
Abstract
The aim of the study was to investigate airway conditioning function and cold hyperresponsiveness in patients with bronchial asthma (BA) and nasal polyps. One hundred and eleven asthma patients with or without chronic polypous rhinosinusitis (CPR) were examined. Respiratory heat exchange and cold airway hyperresponsiveness were assessed using thermometry of expired air during quiet breathing and isocapnic hyperventilation with cold air in comparison with a group of healthy persons. The conditioning nasal function was worsened in BA patients with CPRS. Disorders of nasal heat exchange led to decreased temperature of the exhaled air during quiet breathing and cold hyperventilation. These disorders were closely related to increased frequency and severity of cold airway hyperresponsiveness.
About the Author
E. V. Zakharova
Дальневосточный научный центр физиологии и патологии дыхания СО РАМН
Russian Federation
Russian Federation
References
1. Global Initiative for Asthma: Global strategy for asthma management and prevention: Revised 2006. Available at: www.ginasthma.org
2. Dursun A.B., Sin B.A., Dursun E. et al. Clinical aspects of the link between chronic sinonasal diseases and asthma. Allergy Asthma Proc. 2006; 27: 510–515.
3. Буков В.А., Фельбербаум Р.А. Рефлекторные влияния с верхних дыхательных путей. М.: Медицина; 1980.
4. Плужников М.С. Рязанцев С.В. Роль верхних дыхательных путей в физиологии и патологии бронхолегочной системы. В кн.: Путов Н.В. (ред.). Болезни органов дыхания: Руководство для врачей. М.: Медицина; 1989; т. 1: 101–112.
5. Proctor D.F., Andersen J. The nose: upper airway physiology and the atmospheric environment. Amsterdam: Elsevier Biomedical Press; 1982.
6. Приходько А.Г., Перельман Ю.М. Клинико-функциональная характеристика холодовой гиперреактивности дыхательных путей при хронических болезнях органов дыхания. В кн.: XVI Национальный конгресс по болезням органов дыхания. II Конгресс Евроазиатского респираторного общества, С.-Петербург, 14–17 нояб. 2006 г.: Сборник трудов конгресса. СПб.; 2006. 56.
Review
For citations:
Zakharova E.V. Clinical and functional featuresof respiratory heat exchange and cold airway hyperresponsiveness in patients with bronchial asthma and chronic polypous rhinosinusitis. PULMONOLOGIYA. 2008;(6):59-62. (In Russ.) https://doi.org/10.18093/0869-0189-2008-0-6-59-62
Views:
273
Email this article 