Particularities of asthma occurring in patients with COPD
https://doi.org/10.18093/0869-0189-2008-0-3-35-37
Abstract
Co-morbidity of asthma and COPD requires a special approach to diagnosis and therapy. The aim of this study was to assess clinical and functional features in patients with asthma and COPD. We analysed findings of 21 patients with asthma and COPD (20 males, the average age, 48.5 ± 2.9 yrs, the smoking history, 25.4 ± 6.9 pask-yrs). Spirometry and bronchodilator test with salbutamol, measurement of total serum IgE, absolute count of blood and sputum eosinophils, and SaO2, and skin allergic tests were performed in all the patients. Some patients underwent challenge test with methacholine. History of dyspnea attacks followed allergic disease in 57.1 % and exertional dyspnea in 85.7 % of the patients. Lung function was worse in patients compared to healthy persons (FEV 1 – 92.7 ± 1.9 % vs. 69.4 ± 6.1 %, respectively; FVC – 92.1 ± 1.9 % vs. 69.7 ± 5.3 %, respectively; р < 0.05). SaO2 was also lower (94.4 ± 0.79 % compared to 97.0 ± 1.1 in healthy persons; р < 0.05). A positive bronchodilator response was obtained in 57.1 % of the patients. Co-morbidity of asthma and COPD has more severe course and treatment is less effective compared to the single disease.
About the Authors
K.-M. O. Minkailov
Дагестанская государственная медицинская академия; ДНЦ РАМН
Russian Federation
Russian Federation
E. K. Minkailov
Дагестанская государственная медицинская академия; ДНЦ РАМН
Russian Federation
Russian Federation
Sh. Gh. Kurbanova
Дагестанская государственная медицинская академия; ДНЦ РАМН
Russian Federation
Russian Federation
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Review
For citations:
Minkailov K.O., Minkailov E.K., Kurbanova Sh.G. Particularities of asthma occurring in patients with COPD. PULMONOLOGIYA. 2008;(3):35-37. (In Russ.) https://doi.org/10.18093/0869-0189-2008-0-3-35-37
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