Роль полиморфизма генов в чувствительности к саркоидозу легких
https://doi.org/10.18093/0869-0189-2019-29-5-596-603
Аннотация
В обзоре обобщены сведения о роли полиморфных вариантов генов в формировании иммунного ответа при саркоидозе. Обозначены основные гены-кандидаты, однонуклеотидные замены, которые могут оказывать модулирующее действие на развитие иммунных реакций при данной патологии, а также определять не только восприимчивость людей к возникновению саркоидоза легких, но и оказывать влияние на клинические характеристики течения заболевания.
При поддержке: Финансовое обеспечение исследований осуществлялось из средств федерального бюджета на выполнение государственного задания Федерального государственного бюджетного учреждения науки «Федеральный исследовательский центр “Карельский научный центр Российской академии наук”» (0221-2014-0034).
Об авторах
И. Е. Малышева
Институт биологии Федерального государственного бюджетного учреждения науки «Федеральный исследовательский центр “Карельский научный центр Российской академии наук”»
Россия
Россия
Малышева Ирина Евгеньевна – кандидат биологических наук, старший научный сотрудник лаборатории генетики.
185910, Петрозаводск, ул. Пушкинская, 11.
тел.: (8142) 57-18-79
Л. В. Топчиева
Институт биологии Федерального государственного бюджетного учреждения науки «Федеральный исследовательский центр “Карельский научный центр Российской академии наук”»
Россия
Россия
Топчиева Людмила Владимировна – кандидат биологических наук, ведущий научный сотрудник лаборатории генетики.
185910, Петрозаводск, ул. Пушкинская, 11.
тел.: (8142)57-18-79
Э. Л. Тихонович
Республиканская больница им. В.А.Баранова
Россия
Россия
Тихонович Элла Леонидовна – заведующая отделением респираторной терапии.
185019, Петрозаводск, ул. Пирогова, 3.
тел.: (8142) 76-39-10
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Рецензия
Для цитирования:
Малышева И.Е., Топчиева Л.В., Тихонович Э.Л. Роль полиморфизма генов в чувствительности к саркоидозу легких. Пульмонология. 2019;29(5):596-603. https://doi.org/10.18093/0869-0189-2019-29-5-596-603
For citation:
Malysheva I.E., Topchiyeva L.V., Tikhonovich E.L. A role оf gene polymorphism for susceptibility to pulmonary sarcoidosis. PULMONOLOGIYA. 2019;29(5):596-603. (In Russ.) https://doi.org/10.18093/0869-0189-2019-29-5-596-603
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