Treatment of upper airway diseases in patients with cystic fibrosis
https://doi.org/10.18093/0869-0189-2018-28-6-754-761
Abstract
Chronic rhinosinusitis with nasal polyps (CRS NP) is the most prevalent ear, nose, and throat (ENT) disorder in cystic fibrosis (CF) patients. CRS NP can occur in CF children at the age of ≥ 8 months and becomes the chronic disease. Tenacious secret and bacterial infection cause obstruction, edema and hypoxia of paranasal sinuses and contribute to significant morbidity in CF patients. The active monitoring and treatment of CRS NP aimed at improvement of the aeration of paranasal sinuses, mucociliary clearance, and the control of chronic upper airway infection are necessary. Functional Endoscopic Sinus Surgery (FESS) may be the method of choice if surgical treatment is considered. FESS facilitates paranasal sinuses drainage. Due to recurrent course of CRS NP in most CF patients, lifelong follow-up by an ENT specialist and postoperative management using topical steroids and/or antibiotics are required.
About the Authors
G. L. Shumkova
I.M.Sechenov First Moscow State Medical University (Sechenov University), Healthcare Ministry of Russia; Federal Pulmonology Research Institute, Federal Medical and Biological Agency of Russia
Russian Federation
Competing Interests: No conflict of interest
Russian Federation
Galina L. Shumkova - Researcher, Center of Cystic Fibrosis, Federal Pulmonology Research Institute, Federal Medical and Biological Agency of Russia; Postgraduate Student at Department of Ear, Nose, and Throat Diseases Sechenov University, Healthcare MR
Trubetskaya ul. 8, build. 2, Moscow, 119991, Orekhovyy bul'var 28, Moscow, 115682,tel.: (499) 248-55-38
Competing Interests: No conflict of interest
E. L. Amelina
Federal Pulmonology Research Institute, Federal Medical and Biological Agency of Russia
Russian Federation
Competing Interests: No conflict of interest
Russian Federation
Elena L. Amelina - Candidate of Medicine, Head of Laboratory of Cystic Fibrosis.
Orekhovyy bul'var 28, Moscow, 115682, tel.: (926) 205-03-91
Competing Interests: No conflict of interest
V. M. Svistushkin
I.M.Sechenov First Moscow State Medical University (Sechenov University), Healthcare Ministry of Russia
Russian Federation
Competing Interests: No conflict of interest
Russian Federation
Valeriy M. Svistushkin - Doctor of Medicine, Professor, Director of Clinics of Ear, Nose, and Throat Diseases, Head of Department of Ear, Nose, and Throat Diseases, Sechenov University; Chief Otolaryngologist at the Central Federal District of Russia.
Trubetskaya ul. 8, build. 2, Moscow, 119991, tel.: 499) 248-55-11
Competing Interests: No conflict of interest
S. A. Krasovskiy
Federal Pulmonology Research Institute, Federal Medical and Biological Agency of Russia
Russian Federation
Competing Interests: No conflict of interest
Russian Federation
Stanislav A. Krasovskiy - Candidate of Medicine, Senior Researcher, Laboratory of Cystic Fibrosis.
Orekhovyy bul'var 28, Moscow, 115682, tel.: (495) 965-23-24
Competing Interests: No conflict of interest
N. Yu. Kashirskaya
Federal Medical Genetic Academic Center, Russian Academy of Science
Russian Federation
Competing Interests: No conflict of interest
Russian Federation
Nataliya Yu. Kashirskaya - Doctor of Medicine, Professor, Principal Researcher at Laboratory of Genetic Epidemiology.
Ul. Moskvorech'e 1, Moscow, 1115478, tel.: (910) 440-05-63
Competing Interests: No conflict of interest
E. V. Sin’kov
I.M.Sechenov First Moscow State Medical University (Sechenov University), Healthcare Ministry of Russia
Russian Federation
Competing Interests: No conflict of interest
Russian Federation
Eduard V. Sin’kov - Candidate of Medicine, Associate Professor, Department of Ear, Nose, and Throat Diseases.
Trubetskaya ul. 8, build. 2, Moscow, 119991, tel.: (499) 248-55-38
Competing Interests: No conflict of interest
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For citations:
Shumkova G.L., Amelina E.L., Svistushkin V.M., Krasovskiy S.A., Kashirskaya N.Yu., Sin’kov E.V. Treatment of upper airway diseases in patients with cystic fibrosis. PULMONOLOGIYA. 2018;28(6):754-761. (In Russ.) https://doi.org/10.18093/0869-0189-2018-28-6-754-761
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