Possibilities and limitations of inhaled corticosteroids in the treatment of chronic obstructive pulmonary disease
https://doi.org/10.18093/0869-0189-2018-28-5-602-612
Abstract
Combinations of inhaled corticosteroids (ICS) and long-acting bronchodilators are recommended for those patients with chronic obstructive pulmonary disease (COPD) who did not improve significantly with regular long-acting bronchodilators. ICS are known to increase the risk of pneumonia in elderly patients (over 55 years), current smokers, patients with acute exacerbation of COPD, patients with history of previous pneumonia, patients with body mass index < 25 kg/m2, and patients with dyspnea or severe airflow limitation. The risk-benefit ratio should be considered before initiating the treatment with ICS in COPD patients, particularly in patients with the risk factors of adverse events associated with ICS.
About the Author
I. V. Leshchenko
Ural State Medical University, Healthcare Ministry of Russia;
“Novaya bol’nitsa” Clinical Association LLC
Russian Federation
Russian Federation
Igor' V. Leshchenko, Professor, Department of Phthisiology, Pulmonology and Thoracic Surgery, Ural Federal State Medical University, Healthcare Ministry of Russia; Chief Pulmonologist of Sverdlovsk region and Ekaterinburg, Academic Advisor of “Novaya bol'nitsa” clinical association
ul. Repina 3, Ekaterinburg, 620028, ul. Zavodskaya 29, Ekaterinburg, 620109
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Review
For citations:
Leshchenko I.V. Possibilities and limitations of inhaled corticosteroids in the treatment of chronic obstructive pulmonary disease. PULMONOLOGIYA. 2018;28(5):602-612. (In Russ.) https://doi.org/10.18093/0869-0189-2018-28-5-602-612
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