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Antibacterial inhalation therapy with thiamphenicol glycinate acetylcysteinate in pulmonology

https://doi.org/10.18093/0869-0189-2018-28-4-483-489

Abstract

Thiamphenicol glycinate acetylcysteinate (TGA) is a combination of thiamphenicol, a broad-spectrum antibiotic, and mucolytic drug N-acetylcysteine. This article is a  review of pharmacological, microbiological, and clinical effects of this combined drug.  Inhaled TGA could be considered as a worthy alternative for oral mucolytics and oral  antibiotics in treatment of upper and lower airway diseases, such as acute and chronic  rhinosinusitis, otitis media, tonsillitis, acute bronchitis, and acute exacerbation of chronic bronchitis and chronic obstructive pulmonary disease, in children and adults.

About the Authors

V. A. Kapustina
I.M.Sechenov Federal First Moscow State Medical University (Sechenov University), Healthcare Ministry of Russia
Russian Federation

Candidate of Medicine, Associate Professor, Department No.1 of General Internal Medicine, Medical Faculty

tel.: (499) 245-23-02

ul. Trubetskaya 8, build. 2, Moscow, 119991, Russia



S. I. Ovcharenko
I.M.Sechenov Federal First Moscow State Medical University (Sechenov University), Healthcare Ministry of Russia
Russian Federation

Doctor of Medicine, Professor, Department No.1 of General Internal Medicine, Medical Faculty

tel.: (499) 248-45-23

ul. Trubetskaya 8, build. 2, Moscow, 119991, Russia



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Review

For citations:


Kapustina V.A., Ovcharenko S.I. Antibacterial inhalation therapy with thiamphenicol glycinate acetylcysteinate in pulmonology. PULMONOLOGIYA. 2018;28(4):483-489. (In Russ.) https://doi.org/10.18093/0869-0189-2018-28-4-483-489

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ISSN 0869-0189 (Print)
ISSN 2541-9617 (Online)