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E-cigarette or vaping use-associated lung injury

https://doi.org/10.18093/0869-0189-2026-36-3-513-521

Abstract

Over the past decade, the rapid growth in popularity of electronic nicotine delivery systems has led to an increase in lung injury cases and a new condition known as e-cigarette or vaping use-associated lung injury (EVALI).

The aim of this study was to present the first case of e-cigaretteassociated lung injury reported in a hospital setting.

Results. A young patient was admitted to the hospital on an emergency basis with severe respiratory complaints. Initial radiographic findings were normal. Over the course of one year, the patient developed progressive respiratory failure, leading to widespread pneumofibrosis, which ultimately resulted in death.

Conclusion. Based on the identified combination of emphysema, pulmonary fibrosis, and histologically confirmed alveolitis, along with a history of e-cigarette smoking, a diagnosis of toxic acute lung injury (EVALI syndrome) with a histological pattern of diffuse alveolar damage, resulting in pulmonary fibrosis, was verified.

About the Authors

L. V. Povalyaeva
Federal State Budgetary Educational Institution of Higher Education “Samara State Medical University” of the Ministry of Healthcare of the Russian Federation; State Budgetary Healthcare Institution of the Samara Region “Samara City Hospital No.4”
Russian Federation

Lyudmila V. Povalyaeva, Candidate of Medicine, Associate Professor of the Department of Phthisiology and Pulmonology, Federal State Budgetary Educational Institution of Higher Education “Samara State Medical University” of the Ministry of Healthcare of the Russian Federation; Deputy Chief Physician for Medical Affairs, State Budgetary Healthcare Institution of the Samara Region “Samara City Hospital No.4”

ul. Chapaevskaya 89, Samara, 443099, 

ul. Michurina 125, Samara, 443056



E. A. Borodulina
Federal State Budgetary Educational Institution of Higher Education “Samara State Medical University” of the Ministry of Healthcare of the Russian Federation
Russian Federation

Elena A. Borodulina, Doctor of Medicine, Professor, Head of the Department of Phthisiology and Pulmonology

ul. Chapaevskaya 89, Samara, 443099



B. E. Borodulin
Federal State Budgetary Educational Institution of Higher Education “Samara State Medical University” of the Ministry of Healthcare of the Russian Federation
Russian Federation

Boris E. Borodulin, Doctor of Medicine, Professor, Department of Phthisiology and Pulmonology

ul. Chapaevskaya 89, Samara, 443099



A. T. Kolesnikova
Federal State Budgetary Educational Institution of Higher Education “Samara State Medical University” of the Ministry of Healthcare of the Russian Federation; State Budgetary Healthcare Institution of the Samara Region “Samara City Hospital No.4”
Russian Federation

Anastasia T. Kolesnikova, Candidate of Medicine, Assistant Professor of the Department of Phthisiology and Pulmonology, Federal State Budgetary Educational Institution of Higher Education “Samara State Medical University” of the Ministry of Healthcare of the Russian Federation; Pulmonologist, State Budgetary Healthcare Institution of the Samara Region “Samara City Hospital No.4”

ul. Chapaevskaya 89, Samara, 443099, 

ul. Michurina 125, Samara, 443056



M. A. Vakhlyaev
Federal State Budgetary Educational Institution of Higher Education “Samara State Medical University” of the Ministry of Healthcare of the Russian Federation
Russian Federation

Matvey A. Vakhlyaev – 5th-year student of the Institute of Clinical Medicine

ul. Chapaevskaya 89, Samara, 443099



N. V. Krasnov
Federal State Budgetary Educational Institution of Higher Education “Samara State Medical University” of the Ministry of Healthcare of the Russian Federation; State Budgetary Healthcare Institution of the Samara Region “Samara City Hospital No.4”
Russian Federation

Nikita V. Krasnov, Assistant Professor, Department of Internal Medicine, Federal State Budgetary Educational Institution of Higher Education “Samara State Medical University” of the Ministry of Healthcare of the Russian Federation; Pulmonologist, State Budgetary Healthcare Institution of the Samara Region “Samara City Hospital No.4”; 

ul. Chapaevskaya 89, Samara, 443099, 

ul. Michurina 125, Samara, 443056



E. S. Roslikova
Federal State Budgetary Educational Institution of Higher Education “Samara State Medical University” of the Ministry of Healthcare of the Russian Federation; State Budgetary Healthcare Institution of the Samara Region “Samara City Hospital No.4”
Russian Federation

Elizaveta S. Roslikova, Postgraduate Student, Department of Phthisiology and Pulmonology, Federal State Budgetary Educational Institution of Higher Education “Samara State Medical University” of the Ministry of Healthcare of the Russian Federation; Pulmonologist, State Budgetary Healthcare Institution of the Samara Region “Samara City Hospital No.4”

ul. Chapaevskaya 89, Samara, 443099, 

ul. Michurina 125, Samara, 443056



N. V. Skoptsova
State Budgetary Healthcare Institution of the Samara Region “Samara City Hospital No.4”
Russian Federation

Natal’ya V. Skoptsova, Pulmonologist

ul. Michurina 125, Samara, 443056



A. Y. Ulitina
Federal State Budgetary Educational Institution of Higher Education “Samara State Medical University” of the Ministry of Healthcare of the Russian Federation
Russian Federation

Alina Yu. Ulitina, Infectious Disease Specialist, Assistant Professor, Department of Infectious Diseases with Epidemiology

ul. Chapaevskaya 89, Samara, 443099



References

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Review

For citations:


Povalyaeva L.V., Borodulina E.A., Borodulin B.E., Kolesnikova A.T., Vakhlyaev M.A., Krasnov N.V., Roslikova E.S., Skoptsova N.V., Ulitina A.Y. E-cigarette or vaping use-associated lung injury. PULMONOLOGIYA. 2026;36(3):513-521. (In Russ.) https://doi.org/10.18093/0869-0189-2026-36-3-513-521

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ISSN 0869-0189 (Print)
ISSN 2541-9617 (Online)