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A complex case of differential diagnosis of an atypical form of pulmonary sarcoidosis

https://doi.org/10.18093/0869-0189-2026-36-1-142-146

Abstract

Sarcoidosis is a chronic polysystemic disease of unknown etiology, classified as granulomatosis. Atypical radiological manifestations of the disease may challenge timely diagnosis.

The aim of this work was to present a clinical case demonstrating the capabilities of modern diagnostic methods for disseminated lung diseases. The article presents a clinical case of a 39-year-old patient who was registered at a phthisiological clinic and received anti-tuberculosis therapy at a tuberculosis dispensary. The patient was referred to the Federal State Budgetary Institution “Novosibirsk Tuberculosis Research Institute” of the Ministry of Health of the Russian Federation, where cryobiopsy and pathomorphological examination led to diagnosing sarcoidosis.

Conclusion. Modern high-tech endoscopic equipment allows for more informative investigations and shorter time to correct diagnosis. 

About the Authors

Zh. A. Laushkina
Federal State Budgetary Institution “Novosibirsk Tuberculosis Research Institute” of the Ministry of Health of the Russian Federation
Russian Federation

Zhanna A. Laushkina, Doctor of Medicine, Head of the Research Department of Applied Scientific Research

Okhotskaya 81A, 630040, Novosibirsk

tel.: (383) 203-78-25


Competing Interests:

No conflict of interest has been declared by the authors.



S. V. Sklyuev
Federal State Budgetary Institution “Novosibirsk Tuberculosis Research Institute” of the Ministry of Health of the Russian Federation
Russian Federation

Sergei V. Sklyuev, Candidate of Medicine, Head of the Endoscopy Department

Okhotskaya 81A, 630040, Novosibirsk

tel.: (383) 203-78-25


Competing Interests:

No conflict of interest has been declared by the authors.



I. Yu. Mentyukova-Suzdaltseva
Federal State Budgetary Institution “Novosibirsk Tuberculosis Research Institute” of the Ministry of Health of the Russian Federation

Irina Yu. Mentyukova-Suzdaltseva, Pathologist, Head of the Pathomorphology Department

Okhotskaya 81A, 630040, Novosibirsk

tel.: (383) 203-78-25


Competing Interests:

No conflict of interest has been declared by the authors.



References

1. Ministry of Health of the Russian Federation. [Clinical guidelines: Sarcoidosis]. 2022. Available at: https://spulmo.ru/upload/kr/Sarkoidoz_2022.pdf?ysclid=mj6xnv89ck772241514 [Accessed: August 11, 2025] (in Russian).

2. Speranskaya A.A., Baranova O.P., Kudryashova T.G. et al. [Clinical and radiation features of respiratory sarcoidosis in young people]. Vizualizatsiya v meditsine. 2022; 4 (1): 16–25. Available at: https://ojs3.gpmu.org/index.php/visual-med/article/view/4091 [Accessed: August 11, 2025] (in Russian).

3. Crouser E.D., Maier L.A., Wilson K.C. et al. Diagnosis and detection of sarcoidosis. An official American Thoracic Society clinical practice guideline. Am. J. Respir. Crit. Care Med. 2020; 201 (8): e26–51. DOI: 10.1164/rccm.202002-0251ST.

4. Averyanov AV, Balionis OI, Lesnyak VN. [Atypical CT manifestations of pulmonary sarcoidosis]. Meditsinskiy al'yans. 2021; 9 (3): 71–81. DOI: https://doi.org/10.36422/23076348-2021-9-3-71-81 (in Russian).

5. Lenshin A.V., Ilyin A.V., Perelman Yu.M. [Cavity forms of thoracic sarcoidosis (literature review, clinical and radiological observations)]. Pul'monologiya. 2020; 30 (6): 831–841. DOI: 10.18093/0869-0189-2020-30-6-831-841 (in Russian).


Review

For citations:


Laushkina Zh.A., Sklyuev S.V., Mentyukova-Suzdaltseva I.Yu. A complex case of differential diagnosis of an atypical form of pulmonary sarcoidosis. PULMONOLOGIYA. 2026;36(1):142-146. (In Russ.) https://doi.org/10.18093/0869-0189-2026-36-1-142-146

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ISSN 0869-0189 (Print)
ISSN 2541-9617 (Online)