A case of sufficient intensive therapy of an early postoperative complication after simultaneous thymectomy and O.V.Nikolayev's subtotal thyroidectomy

Abstract

Myasthenia gravis is a progressive autoimmune disease with underlying disorder of neurotransmission from neurons to muscular fibers. Clinical presentations are pathological muscle fatigue leading to paralysis and paresis. Current knowledge of pathophysiological heterogeneity of myasthenia could explain different treatment effects in different patients: complete recovery, insignificant improvement, ineffectiveness or exacerbation with myasthenic crisis. In 60–80% of patients, improvement could be achieved with thymectomy. One of postoperative problems is an absence of a single strategy for therapy with anticholinesterase drugs. The aim of this article was to demonstrate a clinical case of sufficient administration of anticholinesterase drugs in a woman with early complications after simultaneous thymectomy and O.V.Nikolayev's subtotal thyroidectomy.