Inhalation therapy of asthma exacerbations in children
https://doi.org/10.18093/0869-0189-2011-0-5-34-37
Abstract
Summary. This was an open comparative trial of efficacy and safety of combined bronchodilating nebulized therapy in children with moderate to severe bronchial asthma (BA). As a result, combination of ipratropium bromide and short-acting β2-agonists was found to have additive effect on lung function in BA exacerbation.
About the Authors
N. A. GeppeRussian Federation
N. G. Kolosova
Russian Federation
References
1. Национальная программа: Бронхиальная астма у детей. Стратегия лечения и профилактика. 3-е изд. М.; 2008.
2. Чучалин А.Г. (ред.). Рациональная фармакотерапия заболеваний органов дыхания. Руководство для практикующих врачей. М.: Литтерра; 2004.
3. O'Driscoll B.R., Taylor R.J., Horsley M.G. et al. Nebulized salbutamol with and without ipratropium bromide in acute airflow obstruction. Lancet 1989; 1: 1418–1420.
4. Rodrigo G., Castro)Rodriguez J. Anticholinergics in the treatment of children and adults with acute asthma: a systematic review with meta-analysis. Thorax 2005; 60 (9): 740–746.
5. Геппе Н.А. Ингаляционная небулайзерная терапия заболеваний респираторной системы у детей: Практ. руководство для врачей. М.; 2008.
6. Stoodley R.G., Aaron S.D., Dales R.E. The role of ipratropium bromide in the emergency management of acute asthma exacerbation: a meta-analysis of randomized clinical trials. Ann. Emerg. Med. 1999; 34: 8–18.
7. Plotnick L.H., Ducharme F.M. Combined inhaled anticholinergics and beta2-agonists for initial treatment of acute asthma in children. Cochrane Database Syst. Rev. 2000; 4: CD000060.
Review
For citations:
Geppe N.A., Kolosova N.G. Inhalation therapy of asthma exacerbations in children. PULMONOLOGIYA. 2011;(5):34-37. (In Russ.) https://doi.org/10.18093/0869-0189-2011-0-5-34-37