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Inhalation therapy of asthma exacerbations in children

https://doi.org/10.18093/0869-0189-2011-0-5-34-37

Abstract

Summary. This was an open comparative trial of efficacy and safety of combined bronchodilating nebulized therapy in children with moderate to severe bronchial asthma (BA). As a result, combination of ipratropium bromide and short-acting β2-agonists was found to have additive effect on lung function in BA exacerbation.

About the Authors

N. A. Geppe
ГОУ ВПО "Первый Московский государственный медицинский университет им. И.М.Сеченова"
Russian Federation


N. G. Kolosova
ГОУ ВПО "Первый Московский государственный медицинский университет им. И.М.Сеченова"
Russian Federation


References

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3. O'Driscoll B.R., Taylor R.J., Horsley M.G. et al. Nebulized salbutamol with and without ipratropium bromide in acute airflow obstruction. Lancet 1989; 1: 1418–1420.

4. Rodrigo G., Castro)Rodriguez J. Anticholinergics in the treatment of children and adults with acute asthma: a systematic review with meta-analysis. Thorax 2005; 60 (9): 740–746.

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6. Stoodley R.G., Aaron S.D., Dales R.E. The role of ipratropium bromide in the emergency management of acute asthma exacerbation: a meta-analysis of randomized clinical trials. Ann. Emerg. Med. 1999; 34: 8–18.

7. Plotnick L.H., Ducharme F.M. Combined inhaled anticholinergics and beta2-agonists for initial treatment of acute asthma in children. Cochrane Database Syst. Rev. 2000; 4: CD000060.


Review

For citations:


Geppe N.A., Kolosova N.G. Inhalation therapy of asthma exacerbations in children. PULMONOLOGIYA. 2011;(5):34-37. (In Russ.) https://doi.org/10.18093/0869-0189-2011-0-5-34-37

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ISSN 0869-0189 (Print)
ISSN 2541-9617 (Online)