The therapeutic efficacy and pharm acokinetics of theopec in children with bronchial asthma

Abstract

The efficacy of theopec was studied in 67 children aged from 5 to 15 years old suffered from bronchial asthma. A satisfactoiy clinical effect was reached in 80.6% of the patients after the 10th day of treatment with theopec. The favorable influence of theopec on the currence of bronchial asthma was accompanied by the improvement of ventilation function of the lung. During the continuous treatment with theopec the equivalent concentration of theophylline in blood serum were attained after 4 days. The treatment with theopec is recommended in dose 15 to 19 m g/kg/day under the control of theophylline concentration in serum.