The content of the thrombocyte activation factor in serum of patients with bronchial asthma. The trombocytapheresis influence
Abstract
Levels of serum PA F were investigated in patients with various bronchial asthma (BA) forms and in various forms of the clinical manifestation of the disease before and after plateletapheresis (PtA). 15 patients with BA (9 atopic and 6 aspirin-sensitive ones) and 4 healthy donors were examined. The examination demonstrated that only tracks of PA F in the healthy donors are registered but in BA patients the PAF levels were significantly increased. It was found, that in patients with atopic BA the PAF levels were almost by two times higher than in aspirinic BA ones. Moreover, the PAF level in a great extent depends on the disease degree. The serum PAF level was decreased in 42% in average after trobmocytapheresis.
The study demonstrates the features of thrombocytapheresis action and develops the imagination about its action mechanisms.
About the Authors
K. M. Alieva
НИИ пульмонологии М3 РФ, НИИ педиатрии РАМН
Russian Federation
Russian Federation
A. P. Tatarsky
НИИ пульмонологии М3 РФ, НИИ педиатрии РАМН
Russian Federation
Russian Federation
E. N. Arsenieva
НИИ пульмонологии М3 РФ, НИИ педиатрии РАМН
Russian Federation
Russian Federation
L. P. Bykova
НИИ пульмонологии М3 РФ, НИИ педиатрии РАМН
Russian Federation
Russian Federation
B. I. Kruglyi
НИИ пульмонологии М3 РФ, НИИ педиатрии РАМН
Russian Federation
Russian Federation
V. G. Pinelis
НИИ пульмонологии М3 РФ, НИИ педиатрии РАМН
Russian Federation
Russian Federation
A. G. Chuchalin
НИИ пульмонологии М3 РФ, НИИ педиатрии РАМН
Russian Federation
Russian Federation
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Review
For citations:
Alieva K.M., Tatarsky A.P., Arsenieva E.N., Bykova L.P., Kruglyi B.I., Pinelis V.G., Chuchalin A.G. The content of the thrombocyte activation factor in serum of patients with bronchial asthma. The trombocytapheresis influence. PULMONOLOGIYA. 1993;(3):29-31. (In Russ.)
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