Luminol dependent chemiluminescence in diagnostics and control of aspirinic bronchial asthma treatment effectivity
Abstract
The intensity of stimulated with non-specific activators luminol dependent blood hemiluminescence (ChL) was estimated with the presence of non-steroid antiinflammatory drugs (NAID) analgin and aspisol in 52 patients withaspirinic bronchial asthma. The control group contained 10 persons without pathology evidence and 11 patients with atopic bronchial asthma. The ChL coefficient Was 0.59±0.01 in patients with clinical signs of intolerance to NAID during the peroral analgin test and was 1.33+0.02 in the control group. The positive clinical desensitization effect was accompanied with the ChL coefficient increase. Thus, blood predincubation with NAID in patients with aspirinic bronchial asthma decreases the stimulated ChL intensity. The ChL test with NAID can be used to control the desensitisation effectivity.
About the Authors
N. A. DidkovskyRussian Federation
Y. A. Vladimirov
Russian Federation
N. V. Reshetova
Russian Federation
V. K. Treskunov
Russian Federation
I. K. Malashenkova
Russian Federation
V. A. Putvinsky
Russian Federation
V. S. Malinin
Russian Federation
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Review
For citations:
Didkovsky N.A., Vladimirov Y.A., Reshetova N.V., Treskunov V.K., Malashenkova I.K., Putvinsky V.A., Malinin V.S. Luminol dependent chemiluminescence in diagnostics and control of aspirinic bronchial asthma treatment effectivity. PULMONOLOGIYA. 1995;(1):24-28. (In Russ.)