The cholesterolesterase activity of blood monocytes and lipid parameters in patients with chornic bronchitis

Abstract

75 conventional healthy persons and 91 males with CB aged from 20 to 49 years were examined. The patients were divided into groups in relations to the disease duration and the bronchitis entity. The cholesterolesterase activity of blood monocytes was determined by the method of Brecher P. et al., and the content of common cholesterine, triglicerides, cholesterine of high dencity lipoproteids was evaluated with autoanalyser AA-P of “Technicon”. The study revealed that in patients with CB with the increase of the disease duration the activity of cholesterolesterase of blood monocytes was diminished significantly in comparison with the control group. In that time the clinico-morphological entity of CB did not influenced essentially on the ehzyme activity change. In patients with the high clinicolaboratorial activity of the disease the activity of cholesterolesterase was increased significantly during the sharp decrease of the common cholesterol level while the enzyme activity and common cholesterol concentration were diminished in subjects with the similar clinics though without the laboratorial changes.